| Epidemiological and pathogenic study on the outbreak of toxic shock syndrome and meningocephalitis caused by swine streptococcus |
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| 作者姓名： | 唐家琪 白薇 朱进 郭恒彬 胡晓抒 朱凤才 刘光中 |
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| 作者单位： | [1]InstituteofMilitaryMedicineofNanjingCommand,Nanjing210002,China [2]HealthandEpidemicPreventionStationofJiangsuProvince,Nanfing210002,China |
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| 摘 要： | Objective: To reveal the relationship between the biological characteristics of pathogen and the pig-to-human spread of the epidemic and infectious disease in 1998 in East China. Methods: Epidemiological survey, pathological examination of pigs and patients, and pathogen isolation were performed. Results: The disease had a character of quick onset, serious symptoms, short course and high mortality. The clinical manifestations and pathological changes of the disease were high fever, sometimes with nausea, vomiting and diarrhea, then might develop to myositis, fascitis, DIC, multiple organ failure, shock and usually died in 2-3 d. Among 25 patients, 16 manifested clinically as streptococcal toxic shock syndromes and 9 streptococcal meningiocephalitis syndrome. The mortality was 81.25% and 11.11% respectively. Pathogenic bacteria isolated from diseased pigs and patients were found to have some common characteristics in morphology, staining and biological characters. Conclusion: The pathogen isolated from the blood of patients and pigs were identified as streptococci.
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| 关 键 词： | 脑膜脑炎 猪链球菌 中毒性休克 免疫功能 病理机制 |
Epidemiological and pathogenic study on the outbreak of toxic shock syndrome and meningocephalitis caused by swine streptococcus |
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| TANG Jia qi ,BAI Wei ,ZHU Jin ,GUO Heng bin ,HU Xiao shu ,ZHU Feng cai ,LIU Guang zhong Institute of Military Medicine of Nanjing Command,Nanjing ,China Health and Epidemic Prevention Station of Jiangsu Province,Nanjing ,China.Epidemiological and pathogenic study on the outbreak of toxic shock syndrome and meningocephalitis caused by swine streptococcus[J].Journal of Medical Colleges of PLA(China),2004,19(1):59-63. |
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| Authors: | TANG Jia qi BAI Wei ZHU Jin GUO Heng bin HU Xiao shu ZHU Feng cai LIU Guang zhong Institute of Military Medicine of Nanjing Command Nanjing China Health and Epidemic Prevention Station of Jiangsu Province Nanjing China |
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| Institution: | TANG Jia qi 1,BAI Wei 1,ZHU Jin 1,GUO Heng bin 1,HU Xiao shu 2,ZHU Feng cai 2,LIU Guang zhong 2 1Institute of Military Medicine of Nanjing Command,Nanjing 210002,China 2Health and Epidemic Prevention Station of Jiangsu Province,Nanjing 210002,China |
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| Abstract: | Objective: To reveal the relationship between the biological characteristics of pathogen and the pig to human spread of the epidemic and infectious disease in 1998 in East China. Methods: Epidemiological survey, pathological examination of pigs and patients, and pathogen isolation were performed. Results: The disease had a character of quick onset, serious symptoms, short course and high mortality. The clinical manifestations and pathological changes of the disease were high fever, sometimes with nausea, vomiting and diarrhea, then might develop to myositis, fascitis, DIC, multiple organ failure, shock and usually died in 2 3 d. Among 25 patients, 16 manifested clinically as streptococcal toxic shock syndromes and 9 streptococcal meningiocephalitis syndrome. The mortality was 81 25% and 11 11% respectively. Pathogenic bacteria isolated from diseased pigs and patients were found to have some common characteristics in morphology, staining and biological characters. Conclusion: The pathogen isolated from the blood of patients and pigs were identified as streptococci. |
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| Keywords: | acute streptococcal infection streptococcal toxic shock syndrome streptococcal meningiocephalitis syndrome |
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