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Diagnosis and management of late hepatic allograft dysfunction
作者姓名:梅建民  于聪慧
作者单位:DepartmentofHepatobiliarySurgery,GeneralHospitalofBeijingMilitaryCommand,Beijing100700,China
摘    要:Late hepatic allograft dysfunction (LHAD) is common after liver transplantation (LT) and can cause graft failure ,retransplantation ,or even death. A variety of etiologies including rejection ,vascular complications, bile duct complications, recurrent diseases ,infections ,de novo diseases, neoplasms and drug toxicity can result in LHAD. The recurrent diseases have the potential to become the most serious problems facing LT in the future. It is difficult to differentiate late acute rejection from recurrent viral or autoimmune hepatitis. Accurate diagnosis of the cause of LHAD has therapeutic importance.

关 键 词:肝脏移植  肝功能  并发症  血管疾病  自体免疫

Diagnosis and management of late hepatic allograft dysfunction
MEI Jian-min,YU Cong-hui.Diagnosis and management of late hepatic allograft dysfunction[J].Journal of Medical Colleges of PLA(China),2005,20(1):52-57.
Authors:MEI Jian-min  YU Cong-hui
Institution:MEI Jian-min,YU Cong-hui Department of Hepatobiliary Surgery,General Hospital of Beijing Military Command,Beijing 100700,China
Abstract:Late hepatic allograft dysfunction (LHAD) is common after liver transplantation (LT) and can cause graft failure,retransplantation,or even death.A variety of etiologies including rejection,vascular complications,bile duct complications,recurrent diseases,infections,de novo diseases,neoplasms and drug toxicity can result in LHAD.The recurrent diseases have the potential to become the most serious problems facing LT in the future.It is difficult to differentiate late acute rejection from recurrent viral or autoimmune hepatitis.Accurate diagnosis of the cause of LHAD has therapeutic importance.
Keywords:liver transplantation  late hepatic allograft dysfunction  recurrent disease
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