| Killing effect of adenoviral mediated cytosine deaminase gene on human pancreatic cancer cell line PaTu8988 |
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| 作者姓名： | 潘雪 李兆申 许国铭 崔龙 张素贞 龚燕芳 屠振兴 |
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| 作者单位： | PANXue 1，LI Zhao-shen 1，XUGuo-ming 1，CUILong 2，ZHANGSu-zhen 2，GONGYan-fang 1，TU Zhen-xing 1 1 Department of Gastroenterology，2 Department of Surgery，Changhai Hospital，Second Military Medical University，Shanghai200433，China |
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| 摘 要： | Pancreaticadenocarcinomarankssixthofcancer-relateddeathinChina,andittendstobeadvancedatthetimeofpresentation,70%－90%patientsatthetimeofdiagnosishadinoperabledisease.5-Fluorouracil(5FU)iscommonlyusedaloneorwithradiotherapyinthetreatmentofresectablepancreaticcancerandinthepalliationofunresectablepancreaticcancer.Butthecurativeeffectof5FUislimitedbyitssideeffects.Suicidegenetherapyisanewexperimentalformofcancerchemotherapybeingevaluatedinhumantrials.Cytosinedeaminase(CD)isanenzymefoundinava-r…
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Killing effect of adenoviral mediated cytosine deaminase gene on human pancreatic cancer cell line PaTu 8988 |
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| PANXue ,LI Zhao-shen ,XUGuo-ming ,CUILong ,ZHANGSu-zhen ,GONGYan-fang ,TU Zhen-xing.Killing effect of adenoviral mediated cytosine deaminase gene on human pancreatic cancer cell line PaTu8988[J].Journal of Medical Colleges of PLA(China),2001(4). |
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| Authors: | PANXue LI Zhao-shen XUGuo-ming CUILong ZHANGSu-zhen GONGYan-fang TU Zhen-xing |
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| Institution: | PANXue 1,LI Zhao-shen 1,XUGuo-ming 1,CUILong 2,ZHANGSu-zhen 2,GONGYan-fang 1,TU Zhen-xing 1 1 Department of Gastroenterology,2 Department of Surgery,Changhai Hospital,Second Military Medical University,Shanghai200433,China |
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| Abstract: | |
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| Keywords: | pancreatic cancer adenovirus vector cytosine deaminase gene therapy |
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