| 益肾降浊汤对脑缺血再灌注大鼠海马CA1区神经元形态学的影响 |
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| 引用本文： | 高维娟,黄启福,贾旭. 益肾降浊汤对脑缺血再灌注大鼠海马CA1区神经元形态学的影响[J]. 承德医学院学报, 2001, 18(3): 179-182 |
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| 作者姓名： | 高维娟 黄启福 贾旭 |
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| 作者单位： | 1. 承德医学院病理生理学教研室,
2. 北京中医药大学病理学教研室 |
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| 基金项目： | 河北省科技厅科研项目;98276187D; |
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| 摘 要： | 目的:观察益肾降浊汤对大鼠脑缺血再灌注后海马CA1区神经元形态学的影响.方法:用HE染色在光镜下进行观察.结果:与正常对照组相比,模型大鼠术后1天神经细胞水肿,核深染现象明显;7天后神经元密度减轻(P＜0.05),15天时以上病理损伤逐渐加重.治疗组在第1、7、15天海马CA1区神经元病理损伤均轻于模型组,神经元密度较模型组显著增加(P＜0.05).结论:益肾降浊汤可明显减轻脑缺血再灌注后的神经元损伤,对神经元有保护作用.
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| 关 键 词： | 益肾降浊汤 脑缺血再灌注 海马 神经元 形态学 中医药疗法 |
| 文章编号： | 1004-6879(2001)03-0179-04 |
| 修稿时间： | 2001-06-09 |
EFFECT OF YISHEN JIANGZHUO DECOCTION ON THE NEURONS OF HIPPOCAMPAL CA1 REGION MORPHOLOGY OF CEREBRAL ISCHEMIA REPERFUSION RAT |
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| GAO Wei juan ,HUANG Qi fu ,JIA Xu. EFFECT OF YISHEN JIANGZHUO DECOCTION ON THE NEURONS OF HIPPOCAMPAL CA1 REGION MORPHOLOGY OF CEREBRAL ISCHEMIA REPERFUSION RAT[J]. Journal of Chengde Medical College, 2001, 18(3): 179-182 |
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| Authors: | GAO Wei juan HUANG Qi fu JIA Xu |
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| Affiliation: | GAO Wei juan 1,HUANG Qi fu 2,JIA Xu 2 |
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| Abstract: | Objective:To observe the effect of YiShen JiangZhuo decoction on the neurons of hippocampal CA 1 region morphology of cerebral ischemia reperfusion rat.Methods:The neurons of hippocampal CA 1 region were stained with HE 1 and observed using light microscopy.Results:On 1 st day postoperation,the phenomena of nerve cellular edema and hyperchromatosis were patent compared with the control group.On 7 th day postoperation,it was foud that the neuron density had decreased(p<0.05).Above mentioned pathological damage became more and more severe on 15 th day postoperation.The treated group on the 1 st ,7 th ,15 th the neurons of hippocampal CA 1 region pathological damage is lighter than the model group.the neuron density patently increase(p<0.05).Conclusion:YiShen JiangZhuo decoction could dramatically reduce the neural damage induced by cerebral ischemia reperfusion and could protect the neurons. |
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| Keywords: | YiShenJiangZhuo decoction Cerebral ischemia reperfusion Hippocampal Neuron Morphlolgy Rat |
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