不同b值下正常老年前列腺外周带ADC值定量分析

目的分析不同b值下正常老年前列腺的DWI表现,并初步提出正常老年前列腺外周带ADC的参考值范围。方法选取113例60岁以上正常老年前列腺行MRI检查,分别测量不同b值（b=500、800、1000s/mm^2）下前列腺外周带的ADC值,并对其外周带的ADC值进行统计学分析。结果随着b值的增大前列腺外周带ADC值逐渐减小,两两组间比较具有统计学意义（P〈0.05）。不同b值下正常老年前列腺外周带ADC值95%参考值范围分别为：b值=500s/mm^2时（1.26～2.46）×10^-3mm^2/s、b值=800s/mm^2时（1.19～2.29）×10^-3mm^2/s、b值=1000s/mm^2时（1.15～2.17）×10^-3mm^2/s。结论不同b值下正常老年前列腺外周带ADC值有差异,正常老年前列腺外周带ADC参考值范围的提出对前列腺外周带疾病的诊断具有一定的参考价值。

QUANTITATIVE STUDY ON ADC VALUES OF NORMAL PERIPHERAL ZONE WITH OLD MEN UNDER DIFFERENT B-VALUES

Objective To describe diffusion-weighted imaging （DWI ） appearances of the normal elderly prostate under different b-values,And initially proposed the reference range of ADC values of the normal prostate peripheral zone.Methods 113 volunteers were selected,normal prostate over the age of 60 took the MRI examination.ADC values of the Peripheral zone were retrospectively measured under different b values,and statistical analysis the ADC values of the peripheral zone.Results As b value increasing the ADC values of prostate peripheral zone gradually decreases,there was statistically significance between random two groups.The Reference ADC of the peripheral zone of the normal were （1.26～2.46）×10^-3mm^2/s,（1.19～2.29）×10^-3mm^2/s,（1.15-2.17）×10^-3mm^2/s in different b value.Conclusion There are significant difference between the ADC values of Peripheral zone of normal prostate under different b value.Proposing reference range of ADC value of elderly normal prostate peripheral zone has a certain reference value for diagnosis of the prostate diseases of peripheral zone.