首页 | 本学科首页   官方微博 | 高级检索  
检索        

长链非编码RNA在肿瘤中的研究进展
引用本文:谢素红,李智.长链非编码RNA在肿瘤中的研究进展[J].同济大学学报(医学版),2013,34(1):111-115.
作者姓名:谢素红  李智
作者单位:同济大学附属第十人民医院检验科;同济大学附属杨浦区中心医院检验科
基金项目:国家自然科学基金(81171883)
摘    要:长链非编码RNA(long non-coding RNA,lncRNA)在癌症中的研究崭露头角,研究显示其在肿瘤的形成中具有潜在的促癌或抑癌作用。人们发现lncRNA在不同肿瘤中经常出现异常表达,但其具体的生物学功能大多数至今尚不清楚。越来越多研究者相继报道了一些lncRNA在肿瘤中潜在的功能及其分子机制,提示lncRNA在肿瘤的发生、发展中具有重要作用。

关 键 词:长链非编码RNA  肿瘤  研究现状

Research progress of long non-coding RNA in human cancers
XIE Su-hong and LI Zhi.Research progress of long non-coding RNA in human cancers[J].Journal of Tongji University(Medical Science),2013,34(1):111-115.
Authors:XIE Su-hong and LI Zhi
Institution:1.Dept.of Clinical Laboratory,Tenth People’s Hospital,Tongji University,Shanghai 200072,China; 2.Dept.of Clinical Laboratory,Central Hospital of Yangpu District,Tongji University,Shanghai 200090,China)
Abstract:Long non-coding RNAs (lncRNAs) are emerging as new players in the cancer paradigm demonstrating potential roles in both oncogenic and tumor suppressive pathways. These novel genes are frequently aberrantly expressed in a variety of human cancers, however the biological functions of the vast majority remain unknown. Recently, evidence has been accumulated to illustrate the molecular mechanisms by which these RNAs are functioning, so that to provide insight into the functional roles they may play in tumorigenesis.
Keywords:long non-coding RNA  cancer  research status
本文献已被 CNKI 维普 等数据库收录!
点击此处可从《同济大学学报(医学版)》浏览原始摘要信息
点击此处可从《同济大学学报(医学版)》下载免费的PDF全文
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号