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蜂王浆冻干粉对小鼠肿瘤的抑制作用
引用本文:张敬,戴秋萍,刘艺敏,张志强,陈芳,厉曙光.蜂王浆冻干粉对小鼠肿瘤的抑制作用[J].同济大学学报(医学版),2001,22(5):13-14.
作者姓名:张敬  戴秋萍  刘艺敏  张志强  陈芳  厉曙光
作者单位:同济大学医学院预防医学教研室,
摘    要:目的研究蜂王浆冻干粉对小鼠肿瘤的抑制作用.方法按每公斤体重0g、0.25g、0.50g、0.75g设对照及低、中、高3个剂量组,经口给予蜂王浆冻干粉30d后,接种小鼠肉瘤180(S180)和艾氏癌腹水型(EAC)两个瘤种.结果在两次重复的小鼠S180和EAC抑瘤试验中发现中剂量组瘤重明显低于阴性对照组(P<0.05),抑制率可达34%;中剂量组荷瘤小鼠平均生存时间均明显高于对照组(P<0.05).结论蜂王浆冻干粉具有抑制肿瘤的作用.

关 键 词:蜂王浆冻干粉  肿瘤  抑制作用  小鼠
文章编号:1008-0392(2001)05-0013-02
修稿时间:2000年11月8日

Anti-tumor Effects of Lyophilized Royal Jelly
ZHANG Jing,DAI Qiu ping,LIU Yi min,ZHANG Zhi qiang,CHENG Fang,LI Shu guang.Anti-tumor Effects of Lyophilized Royal Jelly[J].Journal of Tongji University(Medical Science),2001,22(5):13-14.
Authors:ZHANG Jing  DAI Qiu ping  LIU Yi min  ZHANG Zhi qiang  CHENG Fang  LI Shu guang
Abstract:Objective Objective To study the anti tumor effects of lyophilized royal jelly.Methods Kuming mice were planted with S180 and EAC tumor cells respectively, after they had been administered orally with daily 0, 0.25, 0.50 , and 0.75 g per kilogram of body weight of lyophilized royal jelly for 30 days, respectively. The above anti tumor experiment was repeated twice.Results The growth of S180 tumor in 0.50 g/kg.bw group was significantly inhibited ( P <0.05) and the inhibitory rate reached 23%. The survival period of the mice bearing EAC tumor in the same dosage group was much longer than that of the control group ( P <0.05).Conclusion These observations suggest that lyophilized royal jelly has an obvious anti tumor effect at certain concentrations.
Keywords:royal jelly  neoplasm  inhibitory effect  mice
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