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ADA,CEA、CA对癌性与结核性胸水的鉴别
引用本文:杨忠民,洪光朝.ADA,CEA、CA对癌性与结核性胸水的鉴别[J].同济大学学报(医学版),2001,22(3):41-42,52.
作者姓名:杨忠民  洪光朝
作者单位:同济大学附属同济医院呼吸科,
摘    要:目的:探讨腺苷氨酶(adnosine deaminase,ADA),癌胚抗原(carcinoembryonic antigen,CEA),糖类抗原(carbohydrate antigen,CA)对癌性与结核性胸水的鉴别意义,方法:对3年来确诊的结核性胸水53例,癌性胸液43例患者的胸水标本进行检测,结果:在结核性胸液中,ADA均值显著高于其在癌性胸水中的均值(P<0.01),而且检测的敏感性,特异性和准确性较其他指标均高(P<0.01),在癌性胸液中,CEA,CA50,CA125,CA199,CA211的均值较它们在结核性胸液中的均值显著升高(P<0.01,P<0.05),结论:在癌性与结核性胸水的鉴别中,对ADA和CA211的联合检测,在胸水性质的鉴别中比其它指标更有意义。

关 键 词:癌性  结核性  胸腔积液  鉴别诊断  ADA  CEA  CA
文章编号:1008-0392(2001)03-0041-02

Discrimination between Carcinous and Tuberculous Pleural Effusion with ADA
YANG Zhong min,HONG Guang chao.Discrimination between Carcinous and Tuberculous Pleural Effusion with ADA[J].Journal of Tongji University(Medical Science),2001,22(3):41-42,52.
Authors:YANG Zhong min  HONG Guang chao
Abstract:Objective To appraise the relationship and discriminate the difference between the tuberculous and the carcinous pleural effusion with Adenosine Deaminase (ADA) Carcinoembryonic Antigen(CEA) and Carbohydrate Antigen(CA).Methods We have examined the samples of 53 cases of tuberculous and 43 cases of carcinous pleural effusion from patients diagnosed in recent three years.Results In tuberculous pleural effusion ,not only the average value of ADA was marked higher than in carcinous( P <0.01),but also the highest in sensitivity?speciality and accuracy( P <0.01). In carcinous pleural effusion,the average value of CEA?CA50?CA125?CA199 and CA211 were higher than those in tuberculous( P <0.01, P <0.05).Conclusion It was a much worthy way for us to distinguish which was carcinous or tuberculous pleural effusion -combined with the ADA and CA211 examination.
Keywords:carcinous  tuberculous  pleural effusion  examination
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