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正常青年人情景记忆编码加工的脑功能磁共振研究
引用本文:席芊,赵小虎,刘君,朱海燕,王培军.正常青年人情景记忆编码加工的脑功能磁共振研究[J].同济大学学报(医学版),2009,30(6):117-120.
作者姓名:席芊  赵小虎  刘君  朱海燕  王培军
作者单位:同济大学附属同济医院医学影像科,上海,200065
基金项目:国家自然科学基金资助项目,上海市科委基础研究重点项目 
摘    要:目的研究汉字情景记忆编码加工时正常青年人大脑皮层的激活情况。方法利用血氧水平依赖性功能磁共振成像技术(blood oxygen level dependent functional MRI,BOLD—fMRJ),采用组块设计的刺激模式,检测20例正常青年人执行汉字情景记忆编码任务时大脑皮层的激活脑区。结果情景记忆编码加工的主要相关激活脑区有左侧前额叶背外侧(BA10)、右侧海马旁回、右侧颞叶梭状回(BA20)、两侧前运动区(BA6)、辅助运动区(BA8)、两倒枕叶(BA19)、右侧项叶(BA7)和两侧小脑半球。结论左右大脑半球在汉字情景记忆编码加工的不同过程中起着不同的作用。

关 键 词:汉字  情景记忆  编码  功能磁共振成像

Encoding of episodic memory in normal young people:an fMRI study
XI Qian,ZHAO Xiao-hu,LIU Jun,ZHU Hai-yan,WANG Pei-jun.Encoding of episodic memory in normal young people:an fMRI study[J].Journal of Tongji University(Medical Science),2009,30(6):117-120.
Authors:XI Qian  ZHAO Xiao-hu  LIU Jun  ZHU Hai-yan  WANG Pei-jun
Institution:(Dept. of Radiology, Tongji Hospital, Tongji University, Shanghai 200065, China)
Abstract:Objective To study the brain activations caused by encoding of episodic memory for Chinese characters in normal young people. Methods The activated brain regions were detected when performing encoding task of episodic memory for Chinese characters in 20 normal volunteers with the blood oxygen level dependent functional MRI technique (fMRI) in block-design stimulating pattern. Results In encoding task, the activated brain regions included left dorsolateral prefrontal gyrus (BA10), right parahippocampal gyrus, right fusiform gyrus (BA20), bilateral pre-central gyrus (BA6), supplementary motor area (BA8), bilateral occipital cortex (BA19), right parietal cortex (BA7) and bilateral cerebellum. Conclusion Left and right hemisphere have different function in various encoding processes of episodic memory for Chinese characters.
Keywords:Chinese characters  episodic memory  encoding  functional MRI
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