| 四联、三联疗法治疗消化性溃疡临床疗效比较 |
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| 引用本文： | 金思思,;王琼,;林贤凡.四联、三联疗法治疗消化性溃疡临床疗效比较[J].中国现代医生,2014(30):139-141. |
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| 作者姓名： | 金思思 ;王琼 ;林贤凡 |
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| 作者单位： | [1]温州医科大学附属第一医院消化内科,浙江温州325000; [2]浙江省温州市人民医院药剂科,浙江温州325000 |
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| 基金项目： | 浙江省自然科学基金（LY12H03003） |
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| 摘 要： | 目的对比四联、三联疗法根除消化性溃疡幽门螺旋杆菌效果,指导临床用药。方法收集2012年10月-2013年5月期间在我院治疗Hp阳性消化性溃疡120例,并随机分组,分别进行含铋剂四联和不含铋剂三联杀Hp治疗2周,分析两组Hp治愈率和根除率。结果四联组患者治疗有效率、幽门螺旋杆菌根除率均好于三联组（P〈0.05）。结论四联疗法对比三联疗法具有疗效高的优点,值得在消化性溃疡患者中推广。
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| 关 键 词： | 消化性溃疡 四联疗法 三联疗法 幽门螺旋杆菌 |
Clinical comparison of the treating effect of four and three therapeutic regimens on gastroduodenal ulcer |
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| Institution: | JIN Sisi, WANG Qiong, LIN Xianfan(1.Department of Gastroenterology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China; 2.Department of Pharmacy, Wenzhou City People＇s Hospital, Wenzhou 325000, China) |
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| Abstract: | Objective To compare the effects of the quadruple, triple therapy for helicobacter pylori in peptic ulcer disease to guide clinical drug use. Methods From October 2012 to May 2013, 120 patients with Hp positive peptic ulcer in our hospital were divided into two groups randomly. Patients treated with the quadruple or triple therapy for two weeks. The cure rates and the eradication rates for Hp were observed during and after treatment. Results The total curative rate and eradication of the quadruple chemotherapy group were better than that of the trigeminy therapy group（P〈0.05）. Conclusion The application of the quadruple therapy has a good clinical therapeutical effect on gastroduodenal ulcer, and it is worthy of being used in a wide range. |
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| Keywords: | Peptic ulcer Quadruple chemotherapy Trigeminy therapy Helicobacter pylori |
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