肺炎支原体及肺炎衣原体感染与儿童慢性咳嗽关系初探

目的分析本地区儿童慢性咳嗽患者肺炎支原体（MP）及肺炎衣原体（CP）感染状况，探讨儿童慢性咳嗽与MP、CP感染的关系。方法收集我院儿科病房2005年3月～2008年9月诊治的慢性咳嗽患儿98例及对照组儿童30例。采用酶联免疫法检测MP-IgM及CP-IgM。结果慢性咳嗽MP-IgM阳性42例，阳性率42．9％；CP—IgM阳性17例，阳性率17．3％；MP-IgM及CP-IgM均为阳性5例（5．1％）；与健康对照组相比有显著性差异（P〈0．01）。结论小儿慢性咳嗽与MP、CP感染有密切关系。在对慢性咳嗽患儿寻找病因、对症治疗的同时，应常规进行MP—IgM及CP—IgM抗体筛查，以便提供循证医学证据。

Relationship between Mycolpasma or Chlamydophila Pneumoniae and Chronic Cough in Children

Objective To ivestigate the role of mycolpasma pneumoniae or ehlamydophila pneumoniae in the pathogenesis of chronic cough in children. Methods Ninety-eight children with chronic cough and 30 healthy children were enrolled in the study. The seroposifivity of MP/CP-IgM was measured by enzyme-linked immunosorbent assay, respectively. Results The incidence of MP/CP infection was significantly higher in study group than that in control group（P〈0.01 ）. Conclusion MP/CP infection has a close relation to chronic cough in children, and the detection of MP/CP-IgM should be a routine item to find the cause of diseases.