Hcy、Hs-CRP、D-D诊断急性脑梗死的临床价值分析

目的 探讨和分析血清同型半胱氨酸（homoeystcine,Hcy）,Hs-C反应蛋白（high sensitive C-reactive protein,Hs-CRP）,D-二聚体 （D-dimer,D-D）诊断急性脑梗死的临床价值.方法 选择2010年2月~2012年2月在我院神经内科住院治疗的急性脑梗死患者38例作为研究对象,分为轻度缺损（≤15分）18例,中度缺损（15～30分）12例,重度缺损（〉30分）8例;另取同期我院健康体检中心的正常体检者32例作为对照组,分别检测各组患者的Hcy、Hs-CRP、D-D的水平.结果 急性脑梗死组的Hcy、Hs-CRP、D-D水平均明显高于对照组,重度脑梗死患者的Hcy、Hs-CRP、D-D水平均明显高于轻度、中度,中度脑梗死患者的Hcy、Hs-CRP、D-D水平均明显高于轻度,差异存在显著性或者极其显著性（P 〈 0.05或P 〈 0.01）.结论 急性脑梗死患者的Hcy、Hs-CRP、D-D 水平均较高,且与疾病的严重程度关系密切,通过检测脑梗死患者的Hcy、Hs-CRP、D-D水平的变化对了解急性脑梗死患者病情的进展及预后具有重要的临床价值.

Clinical value analysis of Hcy,Hs-CRP and D-D in diagnosis of acute cerebral infarction

Objective To explore and analyze the diagnosis value of serum homocysteine （homoeystcine, Hcy）,Hs-C- reactive protein （high sensitive C-reactive protein, Hs-CRP）, D-dimer （D-dimer, D-D） for acute cerebral infarction. Methods From February 2010 to February 2012,38 cases acute cerebral infarction patients were selected as research subjects, 18 cases of mild impairment （~〈 15 points）, moderate impairment （15 to 30 points） in 12 cases,severe de- fects （〉 30 points） in 8 cases. Another year in our hospital health examination center of the normal subjects were se- lected as a control group of 32 patients, Hcy, Hs-CRP, D-D level were measured in each group patients. Results The Hcy, Hs-CRP,D-D of acute cerebral infarction group was significantly higher than the normal control group,severe cerebral infarction in patients with Hcy, Hs-CRP and D-D were significantly higher than mild, moderate, moderate cerebral infarction patients with Hcy, Hs-CRP, D-D water was significantly higher than the slight differences in the presence of a significant or extremely significant （P 〈 0.05 or P 〈0.01 ）. Conclusion Patients with acute cerebral in- farction of Hcy, Hs-CRP, D-D water average higher, and is closely related to the severity of the disease has important clinical value, through the detection of patients with cerebral infarction Hcy, Hs-CRP, DD changes in the level of understanding of the progression of the disease and prognosis of patients with acute cerebral infarction.