97例临终机体应激现象及病理机制初步探讨

目的了解晚期恶性肿瘤和其他临终阶段患者的机体应激现象。方法采用仔细观察、相互应证、分析记录的方法对我院安宁病房2001年1月~2012年12月期间收住的532例临终患者进行观察研究,并从理论上探索和总结。结果发现97例占18.23%的晚期恶性肿瘤和老年衰竭患者在临终阶段发生机体应激现象,其前3位前列腺癌占26.92%,卵巢癌占25.0%,食管癌占25.00%,大致表现为食欲增加、神志转清、能开口说话、梦见亲友、翻身坐起、精神亢奋等,约1~5 d后出现死亡。结论人体在濒临死亡前机体功能从极端衰竭状态、反常性短暂性呈现好转的特殊病理现象,是一种机体的应激现象,可在将近1/5个体中发生,此种现象可持续2~123 h,多与内分泌激素的突然释放和抑制的反馈性生理调节有关。

Initial analysis of pathology excitation mechanism in 97 cases on the phenomenon of stress responses in death stage

Objective To find out stress responses state of death stage of the patients in therioma in later period and other. Methods The methods in careful observation and each other promise analysis record were adopted, in progressed to research the death-stage 532 patients in meprobamate ward from January 2001 to December 2012, and explored summary from theory. Results The phenomenon of stress responses state in death stage of 18.23% patients were discoved, they suffered from therioma in later period and other, among prostate cancer 26.92%, ovary cancer 25.0%, esophagus cancer 25.0%. Appetite increasing, conscioisness clearing, talking, dreaming relative-friend, keeling and siting, spirit raising and so on were showed, they were died in two to five days. Conclusion It is abnormity temporaty specific phenomenon in pathology, appeared before death between human body extreme exhaustion to improvement. The phenomenon related physio-adjustment feed back in releasing and inhibiting suddenly of incretion hormonic.