| 苦参碱联合血塞通治疗慢性乙型肝炎肝纤维化 |
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| 引用本文： | 王希圣. 苦参碱联合血塞通治疗慢性乙型肝炎肝纤维化[J]. 中国现代医生, 2008, 46(32): 86-87 |
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| 作者姓名： | 王希圣 |
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| 作者单位： | 江西省抚州市第一人民医院传染科,江西抚州,344000 |
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| 摘 要： | 目的探讨苦参碱与血塞通注射液合用治疗慢性乙型肝炎肝纤维化的疗效以及可能机制。方法将187例HbsAg、HbeAg、HBV-DNA均为阳性的慢性乙型肝炎患者随机分为治疗组和对照组，治疗组94例应用苦参碱150mg和血塞通400mg静脉点滴，每天1次，8周为一疗程；对照组为常规应用甘利欣30mL和门冬氨酸钾镁注射液20mL，静脉点滴，每天1次，8周为一疗程。治疗前后分别检测HA、LN、PCⅢ、IV-C等肝纤维化指标以及肝功能等，并进行比较。结果与对照组相比，治疗组患者的肝纤维化血清学指标明显下降（P〈0．01）。治疗组治疗前后肝功能改变有统计学意义（P〈0．05～0．01）。结论苦参碱联用血塞通治疗慢性乙型肝炎，可使患者血清肝纤维化指标显著下降，对减轻肝炎症状及肝纤维化、改善肝功能等均有显著疗效。
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| 关 键 词： | 慢性乙型肝炎 苦参碱 血塞通 肝纤维化 |
The Therapeutic Effect of Matrine Combining with Xuesaitong in Patients with Hepatic Fibrosis Induced by Chronic Hepatitis B |
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| WANG Xisheng. The Therapeutic Effect of Matrine Combining with Xuesaitong in Patients with Hepatic Fibrosis Induced by Chronic Hepatitis B[J]. , 2008, 46(32): 86-87 |
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| Authors: | WANG Xisheng |
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| Affiliation: | WANG Xisheng Department of Infections Disease,The First Hospital of Fuzhou,Jiangxi 344000 |
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| Abstract: | Objective To study the efficacy and mechanism of matrine combining with xuesaitong in patients with hepatic fibrosis induced by chronic hepatitis B.Methods 187 masculine patients with HbsAg,HbeAg,HBV-DNA were randomly divided into 2 groups:matrine group received matrine 150mg combining with xuesaitong 400mg,intravenous drip,once daily,8 weeks was a course of treatment.Control group received diammonium glycyrrhizinate injection 30mL and potassium magnesium aspartate injection 20mL.Before and after the treatm... |
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| Keywords: | Chronic hepatitis B Matrine Xuesaitong Hepatic fibrosis |
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