青年人胃癌预后及生存风险相关因素回顾性研究

目的探讨青年人胃癌预后相关的危险因素及生存风险因素。方法对1998年1月～2005年1月我院收治的42例青年胃癌患者的临床资料进行回顾性分析，采用单因素分析及COX生存风险比例模型对患者预后与生存风险相关闪素进行分析。结果患者存活时间范围为6～61个月，中位生存时间12个月，1、3、5年生存率分别为57．1％、25．0％、2．3％。单因素分析显示，患者年龄、肿瘤直径，肿瘤TNM分期、肿瘤分化程度、手术治疗与否、血清白蛋白水平及血红蛋白水平是影响预后的相关因素，COX回归分析显示肿瘤TNM分期、肿瘤分化程度、手术治疗与否及血清白蛋白水平是影响预后的独立因素。结论青年人胃癌生存时间短，肿瘤的生物学特性及治疗是患者生存的相关因素。

Retrospective Study of Survival Risk and Correlation Factor with Prognosis on Young Gastric Cancer

Objective To investigate the survival risk and correlation factor with prognosis on young gastric cancer. Methods 42 eases of young patients with gastric cancer who received in our hospital were seclected and analyzied with retrospective study, survival risk and correlation factor were analysized with univariate analyse and Cox＆apos analyse. Results Survival time of patients was from 6 months to 61 months, median survival time was 12 months,the survival rate was 57.1% in one year,25.0% in 3 years and 2.3% in 5 years. Univariate analyse showed that age, diameter of tumor,TNM stage of tumor, differentiation of tumor, operation therapia,level albumin and hemoglobin were correlation factor with prognosis, Cox＆apo showed that rage of tumor, differentiation of tumor, operation therapia and level of albumin were independent risk factor for prognosis. Conclusion Survival time of young patients with gastric cancer,biological characteristics and treatment was primary correlation factor with prognosis