灰阶超声造影在甲状腺结节诊断中的应用研究

目的:研究甲状腺良恶性结节的灰阶超声造影表现. 方法:对35例患者的40个甲状腺结节术前行常规超声和灰阶超声造影检查, 术后获取病理诊断.结果:良性结节15个,恶性结节25个.良性实性结节超 声造影主要表现为Ⅲ型增强模式;恶性结节36%(9/25)表现为Ⅰ型,24%(6/25)表现为 Ⅱ型,40%(10/25)表现为Ⅲ型.4个良性囊性结节超声造影表现为囊性部分均无增强,实 性部分2个有弥漫增强,2个无增强.结论:灰阶超声造影能反映甲状腺结节的灌注情况,整个无增强或中央区无增强的实性结节可能为恶性.

Qualitative evaluation of thyroid nodules with gray-scale contrast-enhanced ultrasound

OBJECTIVE: To assess the feasibility of gray-scale contrast-enhanced ultrasound for characterizing thyroid nodules. METHODS: Forty thyroid nodules from 35 patients were studied both by conventional techniques and gray-scale contrast-enhanced ultrasound. Of the nodules examined, 15 were benign and 25 malignant. The enhancement of echogenicity was evaluated. The diagnosis was confirmed by surgical biopsy and histopathological examination. RESULTS: The study using gray-scale contrast-enhanced ultrasound showed absent contrast-enhancement in 9 of 25 malignant nodules and 1 of 11 benign solitary nodules; intense enhancement in 6 of 25 malignant nodules, with perfusion defect in the center; diffuse faint enhancement in 10 of 25 malignant nodules and 10 of 11 benign solitary nodules. Benign cystic nodules all showed absent enhancement in the cystic components and 2 of 4 intense enhancement in the solitary components. CONCLUSIONS: Gray-scale contrast-enhanced ultrasonography imaging may be a useful tool for evaluating the perfusion of thyroid nodules. Solitary nodules showing absent enhancement or intense enhancement with absent enhancement in the nodular center may suggest malignant.