| 不同针刺时间对致敏豚鼠血清IL-4和TNF影响的实验研究 |
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| 引用本文： | 邬继红,马惠芳,吕海波,费宇彤,袁红,马文珠.不同针刺时间对致敏豚鼠血清IL-4和TNF影响的实验研究[J].北京中医药大学学报(中医临床版),2006,13(5):10-12. |
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| 作者姓名： | 邬继红 马惠芳 吕海波 费宇彤 袁红 马文珠 |
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| 作者单位： | 北京中医药大学针灸学院,北京,100029 |
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| 摘 要： | 目的 对针刺大椎治疗哮喘的时效性进行初步探讨.方法 以哮喘模型豚鼠为观察对象,随机分为空白组、模型组、每日针刺组、隔日针刺组和隔2日针刺组,选用大椎穴作为治疗穴位,以白细胞介素-4(IL-4)和肿瘤坏死因子(TNF)为观察指标.结果 针刺大椎穴后,各针刺组IL-4含量和TNF含量均有不同程度的下降,隔2日针刺组降低最为明显,与模型组相比有非常显著的差异(P＜0.001).结论 隔2日针刺为最佳治疗时间.
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| 关 键 词： | 哮喘 针刺 大椎 白细胞介素-4 肿瘤坏死因子 针刺时效 针刺时间 豚鼠 血清 影响 实验 研究 guinea pigs levels serum acupuncture different 治疗时间 最佳 差异 程度 含量 结果 观察指标 瘤坏死因子 白细胞介素 |
| 收稿时间： | 2006-05-11 |
| 修稿时间： | 2006-05-11 |
Influence of different acupuncture tine on serum IL-4 and TNF levels in sensitized guinea pigs |
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| WU Ji-hong, MA Hui-fang, LU Hai-bo.Influence of different acupuncture tine on serum IL-4 and TNF levels in sensitized guinea pigs[J].Journal of Beijing University of Traditional Chinese Medicine,2006,13(5):10-12. |
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| Authors: | WU Ji-hong MA Hui-fang LU Hai-bo |
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| Institution: | Beijing University of Chinese Medicine, Beijing 100029 |
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| Abstract: | Objective To investigate the time-effectiveness of acupuncture in the acupoint of Dazhui (GV14) on asthma. Method The asthma model of guinea pigs were randomly divided into group 1 (the blank group), group 2 (the model group), group 3 (acupunctured every day), group 4 (acupunctured every other day) and group 5 (acupunctured every three days). The acupoint of GV14 was chosen as the treatment acupoint and the serum levels of interleukin-4 (IL-4) and tumor necrosis factor (TNF) were observed. Result After acupuncture in GV14 the serum levels of IL-4 and TNF in group 3, 4 and 5 were decreased in varying degrees. The result of group 5 was most significant and there was a great significant difference between group 5 and group 2 (P<0.001). Conclusion Acupuncture given every three days will have the best time-effectiveness. |
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| Keywords: | asthma acupuncture acupoint of Dazhui (GV14) interleukin-4 tumor necrosis factor time-effectiveness of acupuncture |
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