老年高血压病与高血压病合并糖尿病心率变异性和动态血压变化分析

目的探讨老年原发性高血压病（essential hypertension，EH）与EH合并2型糖尿病（diabetes mellitus，type2，T2DM）心率变异性（heart rate variability，HRV）和动态血压（ambulatory blood pressure，ABP）的变化特点。方法对32例EH合并T2DM患者、26例EH患者、22例对照组的HRV和ABP进行比较分析。结果与对照组比较，EH组SDNN（P〈0．01）和HF（P〈0．05）下降，LF（P〈0．05）和LF／HF（P〈0．05）增加。与EH组比较，EH合并T2DM组SDNN州（P〈0．01）和HF（P〈0．05）下降，LF／HF（P〈0．01）增加，且EH合并T2DM组24hSBP（P〈0．05）、dSBP（P〈0．01）和dDBP（P〈0．05）均高于EH组。结论EH患者存在着HRV和血压变异性（blood pressure variability，BPV）异常，糖代谢异常可加重EH的HRV和BPV的异常程度。

Analysis of heart rate variability and ambulatory blood pressure of elderly patients with hypertension and coticurrent hypertension and dlahetes

Objective To investigate the characteristics of heart rate variability（HRV）and ambulatory blood pressure（ABP） of elderly patients with essential hypertension（EH）and EH complicated with diabetes mellitus type 2（T2DM）.Methods The paramcters of HRV and ABP were. compared in 26 eases of EH,32 eases of EH with T2DM and 22 control subjects.Results SDNN（ P 〈 0.01）and HF（ P 〈 0.05）of EH group were significantly lower and LF（ P 〈 0.05） and LF/HF（P 〈 0.05）were significantly higher than those of control group respectively.SDNN（ P 〈 0.01 ）and HF（ P 〈 0.05）of EH ＋ DM group were significantly lower and LF/HF（ P 〈 0.01 ）was significantly higher than those of EH group respeetively.24hSBP（ P 〈 0.05） ,dSBP（ P 〈 0.01）and dDBP（ P 〈 0.05）of EH ＋ DM group were significantly higher than those of Eli group respectively. Conclusion The HRV and blood pressure variability is abnormal in padents with EH, which can be made serious by glycometabolism disorders.