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呼吸指数对慢性肺心病急性加重期呼吸衰竭患者临床意义的评估
引用本文:张伟强.呼吸指数对慢性肺心病急性加重期呼吸衰竭患者临床意义的评估[J].四川医学,2009,30(10):1565-1566.
作者姓名:张伟强
作者单位:梅州市人民医院ICU,广东,梅州,514031
摘    要:目的探讨呼吸指数对慢性肺心病急性加重期呼吸衰竭患者临床意义的评估。方法158例慢性肺心病急性加重期患者测定了肺泡气氧分压(PAO2)和动脉血气,计算呼吸指数(RI),并与同期健康人比较。结果肺心病各组之间、肺心病各组与对照组之间差异均有统计学意义(P〈0.01)。肺心病各组各项指标治疗后与治疗前比较差异均有统计学意义(P〈0.01),与对照组比较差异也有统计学意义(P〈0.01);经单因素相关分析,RI与PaO2、PAO2呈显著负相关(r=-0.954、-0.556,P〈0.01);与PaCO2、A-aDO2呈显著正相关(r=0.726、0.897,P〈0.01);重度呼吸衰竭与中、轻度呼吸衰竭组比较,2个、3个和4个及以上器官衰竭发生率差异均有统计学意义(P〈0.01),病死率差异也有统计学意义(P〈0.01);中度呼吸衰竭组与轻度呼吸衰竭组比较,2个和3个器官衰竭发生率差异有统计学意义(P〈0.01)。结论慢性肺心病急性加重期患者的RI变化与其呼吸衰竭的严重程度一致,RI可作为判断慢性肺心病急性加重期呼吸衰竭程度、病情监测和预后的指标之一。

关 键 词:肺源性心脏病  呼吸衰竭  呼吸指数

Changes of respiratory index in chronic pulmonary heart disease
ZHANG Wei-qiang.Changes of respiratory index in chronic pulmonary heart disease[J].Sichuan Medical Journal,2009,30(10):1565-1566.
Authors:ZHANG Wei-qiang
Institution:ZHANG Wei-qiang. (The People's Hospital of Meizhou,Meizhou , Guangdong 514031, China)
Abstract:Objective To study the changes and the clinical significance of respiratory index(RI) in chronic pulmonary heart disease(CCP). Methods Alveolar PO2(PAO2) and arterial blood gas were measured in 158 cases ofCCP CCP in exacerbation and 50 health persons. The CCP group wasdivided into normal respiratory function,light respiratory failme, moderate respiratory failure and servere respiratory, failure. Results There were significant differences among theose groups. The diferences of the-se index between in before and after treatment. The level of Rl was signifieandy negatively correlated with those of PaO2 , PAO2 and positive correlated with those of PaCO2 and A-aDO2. There were significant differences in the rate of 2,3 or 4 organ failure and mortality between servere respiratory failure and light respiratory failme or moderate respiratory, failure. There were significant differences in the rate of 2 or 3 organ failure between light respiratory failure and moderate respiratory failure. Conclusion The change of RI significantly correlated with the degree of respiratory failure. RI is helpful for evaluating the rspiratory failure and prognosis in CCP.
Keywords:chronic pulmonary heart disease  respiratory failure  respiratory index
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