2002-2011年新疆主动脉夹层的临床特征及变化趋势分析

目的探讨近10年来新疆主动脉夹层的临床特征及变化趋势。方法回顾分析新疆医科大学第一附属医院2002—01～2011—12问连续收治并经影像学检查明确诊断为主动脉夹层的患者653例，对患者的人数、年龄、性别、民族、夹层分型、合并症、治疗方法和死亡人数进行统计分析。结果10年我院共确诊主动脉夹层653例，患者平均年龄（51．7±13．5）岁，40—49岁年龄组发病例数最多，男女之比为3．11：1。少数民族与汉族之比为2．46：1。Debakey分型I型、Ⅱ型、Ⅲ型夹层的构成比分别为31．70％，8．27％，60．03％。主动脉夹层住院病死率12．71％。530例（81．16％）患者有高血压病史或入院时血压增高。在两个5年周期中，主动脉夹层病例数呈逐年递增趋势，后五年收治人数较前5年增长了207％，合并高血压患者较前增加了238％。结论新疆主动脉夹层患者的住院率呈上升趋势，主动脉夹层合并高血压的患者人数明显增加，好发年龄在40一49岁；男女比例接近国外报道。

Change trend and clinical characteristics of aortic dissection in Xinjiang in 2002- 2011

Objective To investigate the clinical features and the change trend of aortic dissection（AD） in Xinjiang during the recent 10 years. Methods Clinical data of 653 patients with AD in First Affiliated Hospital of Xinjiang Medical University from February to December 2011 were analyzed retrospectively. Hospital records and data on prognosis were compared between the two five-year periods. Results Among 653 cases of AD, the male/female ratio was 3.11 ： 1, the minority/Han nationality ratio was 2.46：1, and the mean age was （51.7 ＋ 13.5 ） years. The incidence of hypertension was 81.16% （530/653）. The incidences of Debakey I , Ill, II was 31.70%, 8.27% and 60.03% ,respectively. Intrahospital mortality was 12.71%. The total hospitalized cases increased by 207% in the later five years,and the incidence of hypertension increased by 238%. Conclusion The hospitalized patients with AD increase dramatically, and the incidence of hypertension also increase in AD patients. The AD patients are mainly found in the age of 40 - 49 years. The male/ female ratio is close to the reported.