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小鼠高尿酸血症模型初探
引用本文:金沈锐,郑军,刘绍唐.小鼠高尿酸血症模型初探[J].成都中医药大学学报,1999,22(1):49-50.
作者姓名:金沈锐  郑军  刘绍唐
作者单位:成都中医药大学,基础医学院,四川,成都,610075
摘    要:目的探索建立小鼠高尿酸血症模型的方法。方法使用黄嘌呤600mg/kg和乙胺丁醇250mg/kg,次黄嘌呤600mg/kg和烟酸100mg/kg,ig给药连续5天。结果:给药两组与正常对照组之间,小鼠血尿酸有显著性差异。

关 键 词:痛风  高尿酸血症  小鼠  动物模型
文章编号:1004-0668(1999)01-0049-02

Preliminary Studies on Animal Models of Hyperuricemic Mice
JIN Shenri,ZHENG Jun,LIU Shaotang.Preliminary Studies on Animal Models of Hyperuricemic Mice[J].Journal of Chengdu University of Traditional Chinese Medicine,1999,22(1):49-50.
Authors:JIN Shenri  ZHENG Jun  LIU Shaotang
Abstract:SUMMARY:Purpose: In search of procedures to establish hyperuricemic mice animal models. Way: Using xanthine (600mg/kg) and ethambutol (250mg/kg), hypoxanthine (600mg/kg) to i.g. mice for 5 ays. Result: The animal models of hyperuricemic mice were gotten. Conclusions: These hyperuricemic mice may be serve as animal models for hyperuricemia.
Keywords:Hperuricemia  Mouse  Animal Model  
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