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艾灸对钩端螺旋体感染豚鼠延髓中c-fos表达的影响
引用本文:吴俊梅,魏东焰,黄迪君,张燕华.艾灸对钩端螺旋体感染豚鼠延髓中c-fos表达的影响[J].成都中医药大学学报,1999,22(2):37-40.
作者姓名:吴俊梅  魏东焰  黄迪君  张燕华
作者单位:1. 成都中医药大学针灸推拿学院,四川,成都,610075
2. 四川省第五人民医院
3. 华西医科大学
基金项目::国家自然科学基金资助课题(批准号:39670304)
摘    要:选用39KDa的钩端螺旋体外膜蛋白免疫豚鼠并施予艾灸,研究艾灸对伤害性刺激所和延髓中枢原癌基因c-fos表达的影响。结果表明:灸加OmpL39,单用OmpL39和单纯艾灸均能使豚鼠体内出血程度减轻,抑制内部伤害所致c-fos表达的中枢积累,且灸加OmpL39组作用最强,单用OmpL39组次之,单纯艾灸组再次之。

关 键 词:艾灸  外膜蛋白  原癌基因c-fos  基因表达  免疫保护力  钩端螺旋体
文章编号:1004-0668(1999)02-0037-04
修稿时间:1999-01-11

Efect of Moxibustion to expression of Oblongatal c-fos of Leptospira Infection Guineapigs
WU Jun mei,WEI Dong yan,HUANG Di jun,et al Acupuncture,Moxibustion and Tuina College,Chengdu University of TCM.Efect of Moxibustion to expression of Oblongatal c-fos of Leptospira Infection Guineapigs[J].Journal of Chengdu University of Traditional Chinese Medicine,1999,22(2):37-40.
Authors:WU Jun mei  WEI Dong yan  HUANG Di jun  Acupuncture  Moxibustion and Tuina College  Chengdu University of TCM
Abstract:SUMMARY:The leptospira outer membrane protein of 39 KDa(OmpL39) to inoculate the guinea pigs was chosen,and gave them moxibustion to research the result of moxibustion effecting on the expression of c fos in central nerve system caused by harming stimulation The results showed that OmpL39 with moxibustion,simple OmpL39 and simple moxibustion could all lighten the internal hemorrhage degree,cut down the accumulation of onco gene c fos expressing in central nerve system caused by harming stimulation Furthermore,the action of OmpL39 with moxibustion was the best,simple OmpL39 the second,simple moxibustion the third It was suggested that moxibustion reduced the afference of pathodamage and harming stimulation caused by leptospira in the body by improving the vital Qi,then decreased expression of c fos in the CNS,and promoted the immunity of OmpL39
Keywords:Moxibustion  Outer membrane protein Onco  gene c  fos  expression of gene  immumity  leptospira
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