同型半胱氨酸与血管疾病

同型半胱氨酸(Hcy)的合成与代谢受诸多因素的影响。高Hcy血症通过内皮毒性作用、刺激血管平滑肌增生、促进血栓形成及影响物质代谢等机制诱发动脉粥样硬化及血管疾病,导致高血压、冠状动脉粥样硬化性心脏病、脑梗死等。通过食用富含维生素的食物,口服叶酸及B族维生素等药物,可有效降低血浆Hcy浓度,从而可预防和治疗血管疾病。

Hemocysteine and Vascular Disease

We have read many literatures about Homocysteine(Hcy)and studied the association between blood Hcy level and vascular disease.The metabolism of Hcy was influenced by many factors.High plasma Hcy concentration can influence endothelial,smooth muscle of vessel,metabolism of lipid,protein,glucose and LDL cholesterol.Many studies remain robust in linking elevated plasma Hcy concentration to the development of premature atherosclerosis and thrombosis,and then lead to vascular diseases such as hypertension,corona...