股骨头坏死的关节软骨病变研究进展

股骨头坏死治疗方式的选择,应充分考虑到关节软骨的状况。软骨、软骨下皮质骨及软骨下小梁骨在结构和功能上被看成是一个功能单元体。软骨下小梁骨坏死,既改变了关节软骨的载荷传导与分布途径,使相邻的软骨下皮质骨与软骨易于遭受机械性损伤,也破坏了软骨下区的微循环,影响软骨营养的获得及代谢产物的排出,使相邻的软骨下皮质骨与软骨易于遭受代谢性损伤。股骨头骨坏死的临床研究和实验研究显示,股骨头坏死的骨缺损对覆盖其上的邻近关节软骨的结构和代谢有损害作用。

The Effect of Subchondral Bone Defect in Femoral Head on Structure and Metabolism of Article Cartilage

Viability and function of the articular cartilage must be considered when a femoral head-sparing approach is used to treat osteonecrosis. The cartilage, cortical end plate, and subchondral bone are a functional and structural unit. Osteonecmsis of trabecular bone under articular cartilage,changes the load conduction and contribution of the articular cartilage, as well as affect articular cartilage to acquire nutrition and eliminate metabohc product. The bone defect of osteonecmsis had effect on the structure and metabolism of the articular cartilage near the bone defect, and sugest osteonecrosis at the stage of pro-collapse may affect the cartilage overlying it.