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脑钠肽及N末端脑钠肽前体指导心力衰竭用药的研究进展
引用本文:王子健.脑钠肽及N末端脑钠肽前体指导心力衰竭用药的研究进展[J].医学综述,2013,19(9):1619-1621.
作者姓名:王子健
作者单位:王子健 (昆明医科大学第一附属医院心内科,昆明,650032);
摘    要:心力衰竭是一种严重威胁人类健康和生命的主要疾病之一,具有患病率高、病死率高的特点。测试利钠肽标志物,如脑钠肽或N末端脑钠肽前体水平,已成为心力衰竭患者的诊断和危险分层及预后判断的一个重要工具。然而,监测脑钠肽及N末端脑钠肽前体能否指导慢性心力衰竭的治疗是近几年一直在讨论和争议的话题。该文就脑钠肽及N末端脑钠肽前体的生物学特性、脑钠肽及N末端脑钠肽前体监测对指导心力衰竭患者治疗的进展进行综述。

关 键 词:脑钠肽  N末端脑钠肽前体  心力衰竭  指导治疗

Research Progress of Brain Natriuretic Peptide/N-terminal Pro-brain Natriuretic Peptide Precursor Guiding Heart Failure Medication
WANG Zi-jian,HUA Bao-tong,WANG Qi-xian.Research Progress of Brain Natriuretic Peptide/N-terminal Pro-brain Natriuretic Peptide Precursor Guiding Heart Failure Medication[J].Medical Recapitulate,2013,19(9):1619-1621.
Authors:WANG Zi-jian  HUA Bao-tong  WANG Qi-xian
Institution:.(Department of Cardiology,Kunming Medical University First Affiliated Hospital,Kunming 650032,China)
Abstract:Heart failure is a serious threat to human health and life,and is one of the major diseases with high prevalence and high mortality.Testing for natriuretic peptide markers,such as brain natriuretic peptide(BNP) or N-terminal pro-brain natriuretic peptide,has emerged as an important tool for the diagnosis and risk stratification of patients with heart failure.However,whether the BNP/N-terminal pro-brain natriuretic peptide can guide the treatment of chronic heart failure has been the topic of discussion and controversy in recent years.Here is to make a review on the progress on the biological characteristics of the BNP/N-terminal pro-brain natriuretic peptide and their monitoring to guide the treatment of patients with heart failure.
Keywords:Brain natriuretic peptide  N-terminal pro-brain natriuretic peptide  Heart failure  Guiding treatment
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