精子形态学在男性不育中的研究进展

精子形态是精子的一个重要特征,临床上很多不育患者是由于畸形精子率高导致受精率低或受精失败的。精子形态与精子运动、精子顶体、精子-卵子透明带结合、精子DNA完整性等精子功能呈显著相关性。异常形态精子的受精率、受孕率明显下降。精子形态在辅助生殖技术中也有重要的意义,对于精子畸形率高的患者,可以运用精子形态结合一些精子功能检测来选择体外受精或者卵细胞浆内单精子注射周期治疗。

Study Progresses of Sperm Morphology in Infertile Men

Morphology is an important character of spermatozna. In clinic, the higher rate of teratozo- osperm leads to lower fertility rate or failed ferrtilization. Sperm morphology was correlated with sperm motili- ty, sperm acresome, sperm-zona pellucida interaction, sperm nuclear chmmatin and other sperm fuctions. The fertility rate and conception rate of abnormal spennatozna was obviously decreased. Sperm morphology is use- ful in assisted reproductive technology. To those males who with higher teratozoospermia rate, sperm morphol- ogy combined with other sperm function tests can be used to select the means of medical treatment.