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IL-22的生物学效应及其在哮喘发病中的作用
引用本文:马继龙,彭经纬.IL-22的生物学效应及其在哮喘发病中的作用[J].医学综述,2013,19(11):1997-1999.
作者姓名:马继龙  彭经纬
作者单位:马继龙 (三峡大学仁和医院儿科,湖北,宜昌,443001);彭经纬 (三峡大学仁和医院儿科,湖北,宜昌,443001);
摘    要:支气管哮喘是一种常见的疾病,严重威胁着人类的健康。哮喘的发病与遗传因素和环境因素都有十分密切的关系,其具体机制十分复杂,目前仍不明确。众多细胞及细胞因子都参与哮喘的病变过程,现在发现白细胞介素(IL)22是支气管哮喘发病过程中的一个重要的细胞因子。越来越多的研究表明,哮喘的发病与IL-22密切相关。该文就IL-22的生物学效应及其与支气管哮喘的关系予以综述。

关 键 词:白细胞介素22  Th17细胞  支气管哮喘

The Biological Effects of IL-22 and Its Role in the Pathogenesis of Asthma
MA Ji-long,PENG Jingwei,WANG Min.The Biological Effects of IL-22 and Its Role in the Pathogenesis of Asthma[J].Medical Recapitulate,2013,19(11):1997-1999.
Authors:MA Ji-long  PENG Jingwei  WANG Min
Institution:2. (1. Department of Pediatrics,Three Gorges University Renhe Hospital,Yichang 443001, China;2.Department of Pediatrics,Yichang Central People’s Hospital,Yichang 443003,China)
Abstract:Asthma is a common disease,a serious threat to human health.The pathogenesis of asthma has a close relationship with gene and environment.The process is very complicated,it is not still clear today.Many cells and cytokines participate in the pathological changes of asthma,now the researchers have found IL-22 is an important cell factor of onset of asthma.More and more facts show that the pathogenesis of asthma is related to IL-22.Here is to make a review of the biological effect of IL-22 and its relationship with bronchial asthma.
Keywords:Interleukin 22  Th17 cell  Bronchial asthma
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