| CIK细胞及其抗肿瘤研究进展 |
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| 引用本文： | 储眉,周健.CIK细胞及其抗肿瘤研究进展[J].医学综述,2008,14(15):2264-2266. |
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| 作者姓名： | 储眉 周健 |
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| 作者单位： | 安徽医科大学安徽省口腔医院口腔颌面外科,合肥,230032 |
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| 基金项目： | 国家自然科学基金
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广东省自然科学基金
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深圳市科技局重点基金 |
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| 摘 要： | 细胞因子诱导的杀伤细胞(CIK细胞)是由多种细胞因子,如干扰素γ、重组白细胞介素2、抗CD3McAb等诱导而成的对多种肿瘤具有杀伤活性的细胞毒性T细胞,具有高效的非主要组织相容性复合物限制性溶瘤活性,被认为是抗肿瘤过继细胞免疫治疗的新希望。本文综述了CIK细胞的特点、杀瘤机制和临床应用现状。
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| 关 键 词： | 杀伤细胞 过继免疫治疗 肿瘤 |
Research Advancements in Cytokine-induced Killer Cells and Its Antitumor Activity |
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| CHU Mei,ZHOU Jian..Research Advancements in Cytokine-induced Killer Cells and Its Antitumor Activity[J].Medical Recapitulate,2008,14(15):2264-2266. |
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| Authors: | CHU Mei ZHOU Jian |
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| Institution: | CHU Mei,ZHOU Jian.(Department of Oral , Maxillofacial Surgery,Anhui Oral Medical Hospital,Anhui Medical University,Hefei 230032,China) |
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| Abstract: | Cytokine-induced killer cells are cytotoxic T cells against various tumors,which induced by several cytokines such as IFN-γ,rIL-2,CD3McAb and so on.Their highly efficient tumoricidal effects are non-MHC restricted,which was considered to be hopeful in application for adoptive cellular immunotherapy.This article reviewed the characteristics,mechanisms,research progress and clinical application of CIK cells. |
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| Keywords: | Killer cells Adoptive immunotherapy Tumor |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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