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进展期胃癌内科治疗研究新进展
引用本文:周文杰,蒋敬庭,吴昌平.进展期胃癌内科治疗研究新进展[J].医学综述,2008,14(23):3605-3611.
作者姓名:周文杰  蒋敬庭  吴昌平
作者单位:苏州大学第三附属医院肿瘤生物诊疗中心,江苏,常州,213003
摘    要:胃癌目前是全球第二大癌症死因,总生存率仅为15%~20%。手术是可切除胃癌的根治性治疗的重要手段之一,对于进展期胃癌,即使在胃癌根治术中采用更广泛的淋巴结清扫术也不能改善患者的生存率,多数患者最终死于复发转移。荟萃分析表明辅助放、化疗可提高进展期胃癌的生存率,晚期胃癌姑息化疗可使中位生存期提高到7.5~12个月,含拓扑异构酶Ⅰ抑制剂、伊立替康、紫杉类的化疗方案能进一步提高化疗的有效率,同时新的分子靶向药物治疗将为胃癌综合治疗开辟了新的途径。

关 键 词:胃癌  辅助化疗  分子标靶治疗  进展

Progresses on Medical Treatment of Advanced Gastric Cancer
ZHOU Wen-jie,JIANG Jing-ting,WU Chang-ping.Progresses on Medical Treatment of Advanced Gastric Cancer[J].Medical Recapitulate,2008,14(23):3605-3611.
Authors:ZHOU Wen-jie  JIANG Jing-ting  WU Chang-ping
Institution:Department of Tumor Biological Treatment;the Third Affiliated Hospital of Suzhou University;Changzhou 213003;China
Abstract:Gastric cancer is the second cause of death worldwide at present,and the survival rate is only 15%~20%.Surgery is one of the most important radical treatments in resectable gastric cancer,but for advanced gastric cancer,even more widely lymph node dissection in the operation can't improve the survival rate,and most patients die of recurrence eventually.Meta-analysis shows that adjuvant radiotherapy and chemotherapy can improve the survival rate of advanced gastric cancer.For advanced gastric cancer,palliati...
Keywords:Gastric cancer  Adjuvant chemotherapy  Molecular target therapy  Advanced  
本文献已被 CNKI 维普 万方数据 等数据库收录!
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