产后抑郁症发病机制中生物化学因素的研究进展

产后抑郁症是产褥期发生的抑郁症,是指以往无精神疾病史的患者出现以持续性情感低落为主的精神健康疾患,在发病过程中常常伴随着思维以及行为的改变,是最为常见的一种产褥期精神综合征.产后抑郁不仅对产妇的生活造成巨大影响,对婴儿的正常发育成长也有影响,严重抑制婴儿正常认知的发展.研究产后抑郁症的发病因素对于疾病预防及治疗具有十分重要的意义,该文综合了近几年来研究人员对产后抑郁症发病机制中生物化学因素的研究成果,从激素、神经递质、及其他因子等方面加以综述,为临床治疗提供依据.

Research Progress of Biochemical Factors in the Pathogenesis of Postpartum Depression

Postpartum depression is the depression after the puerperium, which tlrs to the patients without mental disease history with continuous black mood. In the progression of the disease, patients often express change of thinking and behavior,and it is one of the most common puerperal mental syndromes. Post- partum depression not only influerces the normal life of the women, but also suppress the normal growth and development nf the infants,and rstrains the baby＇s normal development ot＂ cognition. To research the patho- genic tactors is important for the prevention and treatment of postpartum depression. Here is to make a review of the results of the biochemical factors of the pathogenesis of the postpartum depression from the perspectives of the change of hormone,neurotransmitter and other factors respectively in the recent years,in nrder to pro- vide lferences for the clinical treatment.