骨性关节炎的病因及治疗进展

骨性关节炎(OA)是骨科常见疾病之一,病变从膝关节软骨退行性改变开始逐步累及软骨下骨质、滑膜、关节囊等关节重要结构,随着分子生物学、免疫学的发展,发现一些细胞因子在其发病过程中起着十分重要的作用,随着医疗技术的不断发展,生物学治疗和药物治疗不断发展。在此就OA的病因及治疗进展进行综述。

Research Development of the Etiology and Treatment of Osteoarthritis

Osteoarthritis(OA) is one of the common orthopedic diseases.Degenerative lesions of knee articular cartilage gradually involve subchondral bone,synovium,joint capsule and other important structures.With the development of molecular biology and immunology,several cytokines are found to play a very important role in the pathogenesis of OA.Along with the continuous development of medical technology,biological and drug therapy is also constantly updated.This article reviews the research development of the etiol...