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三种消化道恶性肿瘤小肠细菌过度生长情况的研究
引用本文:王为,刘峰,徐爱蕾,颜君,蔡娜,葛妍芹.三种消化道恶性肿瘤小肠细菌过度生长情况的研究[J].医学综述,2011,17(6):946-947.
作者姓名:王为  刘峰  徐爱蕾  颜君  蔡娜  葛妍芹
作者单位:中国人民解放军第一六九医院消化内科,湖南,衡阳,421002
摘    要:目的探讨食管癌、胃癌、肝癌三种消化道恶性肿瘤小肠细菌过生长(SIBO)的情况。方法将168例消化道恶性肿瘤患者分为食管癌组、胃癌组、肝癌组三组,通过葡萄糖氢呼气试验(GHBT)分别检测其SIBO情况,并与健康对照组进行组间比较分析。结果三组消化道恶性肿瘤患者与健康对照组的SIBO阳性率及试餐后呼气氢浓度比较差异均有统计学意义(P<0.01)。肝癌组患者的SIBO阳性率及试餐后呼气氢浓度较食管癌组和胃癌组明显增高,比较差异有统计学意义(P<0.05)。结论消化道恶性肿瘤患者容易发生SIBO,特别是肝癌患者尤为明显,通过呼气氢浓度检测,可及时诊断SIBO,有利于解释疾病的部分临床症状,指导调整治疗用药。

关 键 词:消化系统  恶性肿瘤  小肠细菌过生长  葡萄糖氢呼气试验

A Study on Small Intestinal Bacterial Overgrowth in Patients with Three Gastrointestinal Malignancies
WANG Wei,LIU Feng,XU Ai-lei,YAN Jun,CAI Na,GE Yan-qin.A Study on Small Intestinal Bacterial Overgrowth in Patients with Three Gastrointestinal Malignancies[J].Medical Recapitulate,2011,17(6):946-947.
Authors:WANG Wei  LIU Feng  XU Ai-lei  YAN Jun  CAI Na  GE Yan-qin
Institution:WANG Wei,LIU Feng,XU Ai-lei,YAN Jun,CAI Na,GE Yan-qin.(Department of Gastroenterology,the 169th Hospital of PLA,Hengyang 421002,China)
Abstract:Objective To study the small intestinal bacterial overgrowth(SIBO) in patients with esophageal cancer,gastric cancer,and liver cancer.MethodsPatients with gastrointestinal malignancies(n=168) were divided to three groups,namely,esophageal cancer group,gastric cancer group,and liver cancer group.Glucose hydrogen breath test was used to examine the SIBO profile,controlled by that from healthy volunteers.ResultsThe three patient groups had a significantly different SIBO positive rate and expiratory hydrogen co...
Keywords:Digestive system  Malignant tumor  Small intestinal bacterial overgrowth  Glucose hydrogen breath test  
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