| 甘精胰岛素加口服降糖药治疗2型糖尿病105例临床观察 |
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| 引用本文： | 刘红丽,王叶菊.甘精胰岛素加口服降糖药治疗2型糖尿病105例临床观察[J].医学综述,2011,17(23):3670-3671. |
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| 作者姓名： | 刘红丽 王叶菊 |
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| 作者单位： | 陕西省汉中市中心医院内分泌科,陕西,汉中,723000 |
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| 摘 要： | 目的观察预混人胰岛素疗效不佳的2型糖尿病患者转换甘精胰岛素加阿卡波糖治疗后的疗效及安全性。方法选取汉中市中心医院2008年6月至2010年6月住院的2型糖尿病患者105例,既往使用预混人胰岛素30R,血糖控制不佳或频繁出现低血糖者,转换甘精胰岛素加阿卡波糖治疗。12周后观察空腹血糖、餐后2 h血糖、糖化血红蛋白,并记录低血糖发生次数、体质量变化及胰岛素剂量。结果 98例患者空腹、餐后2 h血糖、糖化血红蛋白达标率分别是92%、87%、83%,低血糖发生率明显降低,胰岛素剂量较前减少,体质量无明显变化。结论对于预混人胰岛素治疗欠佳的患者,"2退1"的治疗策略能提供更佳的血糖控制,并减少低血糖的发生率。
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| 关 键 词： | 2型糖尿病 预混人胰岛素30R 甘精胰岛素 阿卡波糖 |
Clinical Observation of 105 Cases with Insulin Glargine Plus Oral Hypoglycemic Drugs for Treating Type 2 Diabetes |
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| LIU Hong-li,WANG Ye-ju.Clinical Observation of 105 Cases with Insulin Glargine Plus Oral Hypoglycemic Drugs for Treating Type 2 Diabetes[J].Medical Recapitulate,2011,17(23):3670-3671. |
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| Authors: | LIU Hong-li WANG Ye-ju |
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| Institution: | LIU Hong-li,WANG Ye-ju.(Department of Endocrinology,Hanzhong Central Hospital,Hanzhong 723000,China) |
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| Abstract: | Objective To observe the therapeutic efficacy and safety of insulin glargine plus acarbose on patients with type 2 diabetes with poor efficacy of premixed human insulin in converted.Methods To select105 patients with type 2 diabetic in Hanzhong Central Hospital from 2008 June to 2010 June inpatient,previous use of premixed human insulin 30R,poor glycemic control or hypoglycemia has emerged frequently,conversion of insulin glargine plus acarbose treatment.After 12 weeks,fasting blood glucose(FBG),2-hour plas... |
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| Keywords: | Type 2 diabetes Premixed insulin 30R Insulin glargine Acarbose |
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