| 细胞因子诱导的杀伤细胞的基础研究新进展 |
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| 引用本文： | 孔炯,蒋敬庭,吴昌平.细胞因子诱导的杀伤细胞的基础研究新进展[J].医学综述,2009,15(13):1938-1941. |
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| 作者姓名： | 孔炯 蒋敬庭 吴昌平 |
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| 作者单位： | 苏州大学第三附属医院肿瘤生物诊疗中心,江苏,常州,213003 |
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| 摘 要： | 细胞因子诱导的杀伤(CIK)细胞是人外周血单个核细胞在体外经多种细胞因子刺激后获得的一群异质细胞,它具有增殖能力强、杀瘤活性高和杀瘤谱广、临床应用不良反应小的特点,是肿瘤过继免疫治疗中更为有效的杀瘤效应细胞。本文综述了CIK细胞的生物学特性、作用机制等基础研究的最新进展。
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| 关 键 词： | 细胞因子诱导的杀伤细胞 过继性细胞免疫疗法 生物学特性 |
Advance In Elementary Research of Cytokine-induced Killer Cells |
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| KONG Jiong,JIANG Jing-ting,WU Chang-ping.Advance In Elementary Research of Cytokine-induced Killer Cells[J].Medical Recapitulate,2009,15(13):1938-1941. |
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| Authors: | KONG Jiong JIANG Jing-ting WU Chang-ping |
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| Institution: | . ( Department of Tumor Biological Treatment, the Third Affiliated Hospital of Suzhou University, Changzhou 213003, China) |
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| Abstract: | Cytokine-induced killer（CIK） cells are a cluster of ailoplasm ceils, which are prepared from the mononuclcar cells of human peripheral blood that might be stimulated by some kinds of cytokincs. The proliferation and cytotoxicity of CIK cells are high, and the side effect is low. CIK ceil is a more effective anti-tumor cffector cell in adoptive immunotherapy. This article reviewed the biological features, anti-tumor activity and other elementary research of CIK cells. |
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| Keywords: | Cytokine-induced killer cells Adoptive immuneotherapy Biological characteristics |
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