首页 | 本学科首页   官方微博 | 高级检索  
检索        

低位直肠癌新辅助放化疗后完全缓解病例的治疗策略分析
引用本文:吴晓宇,姚学权,陈彻,陈志伟,曹勤洪,刘福坤.低位直肠癌新辅助放化疗后完全缓解病例的治疗策略分析[J].南京铁道医学院学报,2014(1):77-80.
作者姓名:吴晓宇  姚学权  陈彻  陈志伟  曹勤洪  刘福坤
作者单位:江苏省中医院消化肿瘤外科,江苏南京210029
摘    要:目的:探讨低位直肠癌新辅助放化疗后完全缓解病例的治疗策略。方法:对我院接受新辅助放化疗的147例Ⅱ、Ⅲ期低位直肠癌患者的临床、病理资料进行回顾性分析。结果:新辅助放化疗后125例(85.03%)获得症状缓解,14例(9.52%)术后病理完全缓解(病理分期为pT0N0M0),其中5例行术后辅助化疗,未出现术后复发转移;其余9例未行术后治疗,有3例(33.3%)出现术后转移。结论:新辅助放疗可使低位直肠癌肿瘤缩小,临床症状大部分缓解,病理降期,部分患者可达到病理完全缓解,但对完全缓解病例,术后仍需行辅助化疗。

关 键 词:直肠癌  新辅助放化疗  病理完全缓解

Treatment strategy of complete response cases after neoadjuvant radiotherapy in mid-low rectal cancer
WU Xiao-yu,YAO Xue-quan,CHEN Che,CHEN Zhi-wei,CAD Qin-hong,LIU Fu-kun.Treatment strategy of complete response cases after neoadjuvant radiotherapy in mid-low rectal cancer[J].Journal of Nanjing Railway Medical College,2014(1):77-80.
Authors:WU Xiao-yu  YAO Xue-quan  CHEN Che  CHEN Zhi-wei  CAD Qin-hong  LIU Fu-kun
Institution:(Department of Digestive Oncology Surgery,Jiangsu Province Hospital of Traditional Chinese Medicine ,Nanjing 210029, China)
Abstract:Objective: To discuss the treatment strategy of complete clinical response cases after neoadjuvant chemoradiotherapy in mid-low rectal cancer. Methods: The clinical and pathological data of 147 cases with stage 2 or 3 mid-low rectal cancer was analyzed during the period of Jan. 2001 to Dee. 2012. Result: 6 to 8 weeks after the chemoradiotherapy,86 cases had clinical syndrome response, and 16 had complete clinical response. 14 cases had complete pathological response after surgery( the pathological studies showed pT0N0M0) , among which 5 cases had postoperation chemotherapy, and there were no recurrence. However, other 9 cases had no treatment after the surgery, and 3 of them had recurrence. Conclusion: The neoadjuvant radiotherapy could shrink the neoplasm, greatly release the clinical syndrome, and demote the pathological stage. Part of the patients could get complete response. But for those patients who got complete pathological response after surgery, they still had to accept postoperative chemotherapy.
Keywords:rectal cancer  neoadjuvant chemoradiotherapy  pathologic complete response
本文献已被 维普 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号