胺碘酮与毛花苷丙对阵发性非瓣膜病心房颤动患者心室率的影响

目的:探讨胺碘酮和毛花苷丙对阵发性非瓣膜病心房颤动心室率的影响。方法:房颤发作在48h以内的患者,随机分为胺碘酮组、毛花苷丙组和维生素C组,分别静脉推注胺碘酮、毛花苷丙及维生素C,观察房颤转复及心室率的变化。结果:治疗后毛花苷丙组、胺碘酮组和维生素C组心室率下降分别为40.6%、24.1%和7.8%;转复为窦性心律毛花苷丙组、胺碘酮组和维生素C分别为39.4%、59.4%和35.5%。结论:毛花苷丙对阵发性房颤减慢心室率作用优于胺碘酮,但转复为窦性心律低于胺碘酮。

The influcence of amiodarone and lanatoside on ventricular rate of paroxysmal atrial fibrillation in non-rheumatic patients

Objective : To investigate clinical efficacies of amiodarone and lanatoside in treating paroxysmal atrial fibrillation in non-rheumatic patients .Methods: The duration of atrial fibrillation before enrollment was 48 h , Patients were randomly divided into amiodarone group,lanatoside group, and vitaminC group . Miodarone , lanatoside and vitaminC were given intravenously .The patients were monitored for rhythms , heart rate , blood pressure and adverse drug reactions during study . Results: The ventricular rate of after treatment decreased by 40.6% in lanatoside group , amiodarone group decreased 24.1% and vitaminC group decreased by 7.8% ; The success rate of cardioversion for atrial fibrillation was 39.4% in anatoside group , amiodarone group was 59.4% and vitaminC group was 35.5% .Conclusion: Lanatoside seems more effective than amiodarone in controlling ventricular rate in atrial fibrillation ,while amiodarone is more effective in reverting atrial fibrillation.