| 8Hz 130dB次声作用对大鼠肾及肾上腺结构的影响 |
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| 引用本文： | 杨芳,路国华,铁茹,于军,刘利兵.8Hz 130dB次声作用对大鼠肾及肾上腺结构的影响[J].陕西医学杂志,2010,39(5):539-540,551. |
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| 作者姓名： | 杨芳 路国华 铁茹 于军 刘利兵 |
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| 作者单位： | 1. 第四军医大学基础部教学实验中心,西安,710032
2. 第四军医大学生物医学工程系 |
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| 摘 要： | 目的:观察大鼠暴露于8Hz,130dB次声不同时间后肾及肾上腺的病理改变,并探讨损伤意义。方法:将36只大鼠随机分为6组,分别为对照组(1组)与次声暴露实验组(5组),每组6只。给实验组以8Hz,130dB次声作用分别持续1,7,14,21和28d,2h/d,取动物标本,常规HE染色显微镜下观察大鼠肾及肾上腺组织的病理改变。结果:经过暴露于8Hz,130dB次声后,大鼠肾上腺结构同对照组,仅细胞内脂滴增加,增加程度与暴露时间有关。实验组大鼠与对照组相比,明显出现肾血管扩张充血,肾小管上皮细胞肿胀,其程度亦与暴露时间有关。结论:次声可引起肾脏及肾上腺组织的损伤,损伤和次声暴露时间有关。
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| 关 键 词： | 肾/病理学 肾上腺/病理学 声刺激 动物 实验 大鼠 |
Effects of infrasound with 8 Hz/130 dB on the structure of rat kidney and adrenal |
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| Institution: | Department of Experimental Teaching Center,the Fourth MilitaryMedical University(Xi\'an 710032)Yang Fang Lu Guohua Tie Ru et al |
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| Abstract: | Objective:To observe the pathological changes into the rat's kidney and adrenal gland under different times after being exposed in the infrasound with 8 Hz/130 dB,and to explore effects and significance of it.Methods:36 Sprague-Dawley rats were randomly divided into six groups in average,including one normal control group and five infrasound exposed experimental groups.The five experimental groups were respectively exposed in the infrasound with 8 Hz/130 dB for 2 hours per day every 6 days one month,and the... |
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| Keywords: | Kidney/pathology Adrenal glands/pathology Acoustic stimulation Animal laboratory Rat |
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