钛网应用于即刻种植骨缺损骨再生的实验研究

目的 通过动物实验观察钛网联合引导骨组织再生技术(GBR)在不同植体即刻种植周围骨缺损骨再生过程中的实际成骨效果.方法 6只成年健康比格犬,拔除双侧下颌2、3、4前磨牙,一侧植入韩国DIO植体4枚,另一侧植入ITI植体4枚.每颗植体周围制作垂直-水平联合型骨缺损,48枚植体按照处理方法不同分为4组:对照组、GBR组、钛网+骨粉组、钛网+GBR组.6个月后处死实验犬,通过直观测量、硬组织切片和新生骨形成率比较各组骨再生效果.结果 酸蚀喷砂(SLA)表面的植体周围骨再生各项指标均明显优于可吸收研磨介质(RBM)表面;组间相比差异均有统计学意义(P<0.05),钛网+GBR组骨再生效果最佳,GBR组和钛网+骨粉组次之,对照组最差,其中GBR组和钛网+骨粉组差异无统计学意义.结论 SLA表面处理方法有利于即刻种植周围骨缺损的骨整合;钛网联合GBR技术作为一种即刻种植周围骨缺损骨再生的新方法,效果稳定可靠.

The experimental study of titanium mesh applied to bone regeneration in immediate implant bone defect

Objective To observe the effect of titanium mesh combined with guided bone regeneration technique (GBR) technique in the bone regeneration of immediate implantation of bone defect around titanium mesh.Methods 6 healthy adult beagle dogs were 2,3,4 mandibular premolars,DIO implant was implanted into one side of South Korea 4,the other side of the implantation of ITI implants 4.Each implant makingcombined vertical horizontal bone defect,48 implants according to the differenttreatment methods were divided into four groups: control group,GBR group,titanium mesh bone and titanium mesh group+GBR group.After 6 months,the experimental dogs were sacrificed and the effect of bone regeneration was compared between the two groups by visual measurement,hard tissue section and new bone formation rate.Results Sandblasting etching(SLA) peri implant bone regeneration indicators were significantly better than the absorption of grinding medium surface treatment group(RBM) surface treatment group;group compared to find differences between the groups were statistically significant(P<0.05),titanium mesh group+GBR bone regeneration effect is the best,GBR group and titanium mesh bone meal+group the control group is the worst,there was no significant difference between GBR group and titanium mesh+bone meal group.Conclusion The SLA surface treatment method is beneficial to the immediate implantation of bone defect around bone;titanium mesh combined with GBR technology as a new method of immediate implantation of bone defect around bone defect,the effect is stable and reliable.