非小细胞肺癌初诊患者淋巴结清扫数量及其远期疗效分析

目的研究非小细胞肺癌初诊且未见淋巴结转移患者淋巴结清扫数量与生存率之间的关系及其远期疗效,为临床治疗初诊非小细胞肺癌提供依据。方法选择2003年1月-2008年12月在我院初诊且未发生淋巴结转移的148例非小细胞肺癌患者的病历资料,研究其临床病理、淋巴结清扫数量与1年、3年、5年生存率之间的关系。结果患者淋巴结清扫数量越多,其5年生存率越高。T分期、肿瘤直径、淋巴结清扫数量与其5年生存率之间存在着显著的正相关关系。淋巴结清扫数量、清扫站数、T分期是影响患者远期疗效的独立预后因素。T分期相同的患者淋巴结清扫数量越多,其5年生存率越高;T1-T2期淋巴结清扫数量≤10枚的患者其预后显著不如清扫数量〉10枚的患者（P〈0.05）;T3期淋巴结清扫数量≤15枚的患者其预后显著不如清扫数量〉15枚的患者（P〈0.05）。结论非小细胞肺癌初诊患者淋巴结清扫数量与其远期疗效呈现明显的正相关关系。

The Long-Term Curative Effects and Number of the Lymph Node Cleaning in Patients with Non-Small Cell Lung Cancer

Objective To study the number of the lymph node cleaning in the patients with the early diagnosis of non-small cell lung cancer patients and no lymph node metastasis, the relation between the number and the survival rate,and the long-term effects of it which can provide the basis for the clinical treatment of non-small cell carcinoma. Methods 148 cases of non-small cell lung cancer without lymph node metastasis in our hospital from January 2003 to December 2008 were selected. And the relation between the clinical pathology, number of lymph node cleaning and 1-year, 3-years, and 5-year survival rates were analyzed. Results The more the number of the lymph node cleaning was, the higher the 5-year survival rate was. The T-stage, tumor size, lymph node dissection and 5-years survival rate were positively correlated. The numbers of lymph node dissection,cleaning station number and T-stage were the independent prognostic factors associated with long-term results. In the patients with the same T-stage,the more lymph node dissection cleaned, the higher the 5-year survival rate was. And if the number of lymph node cleaning of the T1 - T2 stage in the patients was ≤ 10, the patients had poor prognosis than those patients whose cleaning number〉10 （P〈0.05）. If the number of lymph node dissection of the T3 stage 415,the patients had poor prognosis than those patients whose number of cleaning of more than 15 （P〈0.05）. Conclusion The number of lymph node cleaning in patients with non-small cell lung cancer is positively correlated with the long- term curative effect.