盐城市区及东台市精神分裂症患者纳入严重精神障碍管理后的转归情况调查

目的调查盐城市区及东台市精神分裂症患者纳入严重精神障碍管理后的转归情况。方法选取2016年9月至2017年9月盐城市区及东台市符合"ICD-10"精神分裂症诊断标准的657例患者作为研究对象,根据是否同意参与严重精神障碍管理分为研究组(n=603,同意参与)和对照组(n=54,不同意参与)。研究组采用严重精神障碍管理治疗工作规范进行严重精神障碍管理,对照组未进行相关管理。分别在入组前、入组后6个月、1年、2年和3年采用PANSS、TESS、ADL进行评估,并统计两组1年内再住院情况。结果研究组共402例患者未再次住院,占比66.67%;180例多次住院,占比29.85%,平均住院次数为(2.94±0.38)次;21例长期住院,占比3.48%。对照组共25例患者未再次住院,占比46.30%;20例多次住院,平均住院次数为(3.52±0.40)次;9例长期住院,占比16.67%。研究组再住院情况明显优于对照组(P<0.05)。两组患者入组前PANSS、TESS、ADL评分比较差异无统计学意义;入组后,两组患者PANSS、TESS、ADL评分均呈降低的趋势,且研究组入组后6个月、1年、2年和3年TESS、ADL评分均低于对照组(P<0.05),研究组入组后1、2、3年PANSS评分低于对照组(P<0.05)。结论盐城市区及东台市精神分裂症患者纳入严重精神障碍管理后得到规范的管理与治疗,患者再入院次数明显减少,精神症状、药物不良反应和功能缺失明显好转。

Investigation on the outcome of schizophrenic patients in Yancheng City and Dongtai City after being included in the management of severe mental disorders

Objective To investigate the outcome of schizophrenic patients in Yancheng and Dongtai after being included in the management of severe mental disorders. Methods 657 patients who met "ICD-10" diagnostic criteria for schizophrenia in Yancheng City and Dongtai City from September 2016 to September 2017 were selected as the research subjects. According to whether they agreed to participate in the management of severe mental disorders, they were divided into the study group(n=603, agreed to participate) and the control group(n=54, disagreed to participate).The study group used the standard of management and treatment of severe mental disorders to manage severe mental disorders, while the control group was not managed. PANSS, TESS and ADL were used for evaluation before enrollment, 6 months, 1 year, 2 years and 3 years after enrollment,and the rehospitalization within 1 year was counted. Results 402 patients in the study group were not hospitalized again, accounting for 66.67%;180 cases were hospitalized for many times, accounting for 29.85%. The average number of hospitalizations was(2.94±0.38) times;21 cases were hospitalized for a long time, accounting for 3.48%. In the control group, 25 patients were not hospitalized again, accounting for 46.30%;The average number of hospitalizations was(3.52 ± 0.40) times;9 cases were hospitalized for a long time, accounting for 16.67%. The rehospitalization in the study group was significantly better than that in the control group(P<0.05). There was no significant difference in PANSS, TESS and ADL scores between the two groups before enrollment;the scores of PANSS, TESS and ADL in the study group were lower than those in the control group 6 months, 1 year, 2 years and 3 years after enrollment(P<0.05), and the scores of PANSS in the study group were lower than those in the control group 1 year, 2 years and 3 years after enrollment(P<0.05). Conclusion The schizophrenic patients in Yancheng city and Dongtai city have received standardized management and treatment after being included in the management of severe mental disorders. The number of readmissions has been significantly reduced, and the mental symptoms, adverse drug reactions and functional deficits have been significantly improved.