| 银屑病患者白介素8的观察 |
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| 引用本文： | 郑淑云,商刚.银屑病患者白介素8的观察[J].哈尔滨医科大学学报,1997,31(4):309-310. |
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| 作者姓名： | 郑淑云 商刚 |
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| 作者单位： | [1]哈尔滨医科大学一院皮肤科 [2]哈尔滨二四二医院皮肤科 |
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| 摘 要： | 对４３例银屑病患者，应用ＥＬＩＳＡ法检测了白介素８（ＩＬ－８）的血清含量，同时对其中１２例患者，应用免疫用化技术，观察了ＩＬ－８在其皮损及非皮损区的染色强度。结果表明，银屑病患者血清ＩＬ－８含量明显高于正常人，增高程度与银屑病面积严重程度系数积分相关；皮损处ＩＬ－８染色强度高于非皮损区和正常人皮肤。提示ＩＬ－８在银屑病的发生发展上具有一定作用。
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| 关 键 词： | 银屑病 白介素8 免疫功能 |
Observation of Interleukin 8 in Psoriatic Patients |
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| Zheng Shuyun et al.Observation of Interleukin 8 in Psoriatic Patients[J].Journal of Harbin Medical University,1997,31(4):309-310. |
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| Authors: | Zheng Shuyun |
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| Abstract: | Serum level of Interleukin 8(IL 8) in 43 patient with psoriasis vulgaris was examined with ELISA,and we used an immunohistochemistry technique to investigate IL 8 in the skin lesions and uninvolved psoriatic epidermis from 12 patients of them.The results indicated that the mean serum level of IL 8 in psoriatic patients was remarkedly higher than that in controls and related to psoriasis area and severity index(PASI) score.In addition,the IL 8 staining was significantly increased in skin lesions.It is suggested that IL 8 may play an important role in the happen and the development of psoriasis. |
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| Keywords: | Psoriasis Interleukin8 Immunologic function |
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