首页 | 本学科首页   官方微博 | 高级检索  
检索        

羧甲基茯苓多糖的制备及抗肿瘤药效学研究
引用本文:程金生,赵进,黄徽.羧甲基茯苓多糖的制备及抗肿瘤药效学研究[J].右江医学,2008,36(4).
作者姓名:程金生  赵进  黄徽
作者单位:1. 右江民族医学院药学系,广西百色,533000
2. 广西万山香料有限公司,广西钦州,535400
基金项目:科技部科技支撑计划,广西教育厅科研项目,右江医学院重点基金
摘    要:目的探讨羧甲基茯苓多糖的制备方法及其抗肿瘤活性。方法在卤代酸存在下一步法简便制备羧甲基茯苓多糖,并分别研究其体内、体外抗肿瘤活性。结果同对照组相比,羧甲基茯苓多糖在抑制昆明种小鼠H22肝癌细胞及小鼠肿瘤U-14细胞活性方面具有显著效果。结论通过简便方法制备得到了可显著提高荷瘤小鼠免疫力的羧甲基茯苓多糖,适当剂量的羧甲基茯苓多糖具有良好的抗肿瘤活性。

关 键 词:羧甲基茯苓多糖  制备  抗肿瘤活性

Facile Preparation of Carboxymethyl Pachmaran and the Observation on its Anti-tumor Effects
CHENG Jinsheng,ZHAO Jin,HUANG Hui.Facile Preparation of Carboxymethyl Pachmaran and the Observation on its Anti-tumor Effects[J].Youjiang Medical Journal,2008,36(4).
Authors:CHENG Jinsheng  ZHAO Jin  HUANG Hui
Institution:CHENG Jinsheng1,ZHAO Jin1,HUANG Hui2(1.School of Basic Medical Science,Youjiang Medical College for Nationalities,Baise 533000,2.Guangxi Wanshan Spice Co,Ltd,Qinzhou 535400)
Abstract:Objective To study the preparation and the anti-tumor effects of carboxymethyl pachyman.Methods Carboxymethyl pachmaran was prepared conveniently in one-step process with the presence of halogenated acid.The anti-tumor effects of carboxymethyl pachmaran in vivo and in vitro were studied respectively.Results There were significant effect of the carboxymethyl pachyman for inhibition on murine 22 hepatocarcinoma cell and murine U-14 Cancer Cells comparing with control group.Conclusion Carboxymethyl pachyman ca...
Keywords:carboxymethyl pachyman  preparation  anti-tumor effect  
本文献已被 CNKI 维普 万方数据 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号