急性脑梗塞与脑出血危险因素的对比研究

目的通过对脑卒中资料的分析,观察患者临床资料、生化指标与脑卒中患者的关系,并对脑梗塞与脑出血的危险因素进行比较。方法对本院收治的卒中患者408例,其中脑梗塞281例,脑出血127例,均预先对各项资料进行编码,输入计算机数据库。所有患者均进行系统的临床和辅助检查,脑卒中诊断经过磁共振或CT确诊。结果(1)高血压、吸烟是脑卒中最重要的危险因素。(2)与脑梗塞相比,吸烟(OR=0.226,95%CI=0.107-1.623)、糖尿病病史(OR=0.094,95%CI=0.023-2.401)、心脏病病史(OR=0.046,95%CI=0.236-0.905)对脑出血的危险较小;高血压病史(OR=1.096,95%CI=0.542-0.895)是脑出血唯一危险因素。结论高血压、吸烟是脑卒中最重要的危险因素,脑梗塞与脑出血的危险因素并不完全一致。

Risk factors in patients of China with cerebral infarction versus intracerebral hemorrhage

Objective To evaluate the frequency of various risk factors for overall stroke and to identify risk factors for cerebral infarction(CI) versus intracerebral hemorrhage(ICH) of China.Methods Data from 408 patients,consisting of 281 patients with CI and 127 patients with ICH,were taken hospitalization from Department of Neurology of Affiliated First Hospital of Ningxia Medical College from October 2004 to October 2006,were examined by clinical diagnosis and brain CT or MRI got final diagnosis.Systematic investigations were performed on each patient.Results Hypertension and smoking were the most prominent factor for overall stroke followed by family history of hypertension.In all patients,the factors significantly associated with ICH as opposed CI were history of hypertension(OR=1.096,95%CI=0.542-0.895) and were not smoking(OR=0.226,95%CI=0.107-1.623),history of diabetes mellitus(OR=0.094,95%CI=0.023-2.401) and history of heart disease(OR=0.046,95%CI=0.236-0.905) by multivariate analysis.Conclusion Hypertension and smoking were the most prominent factor for overall stroke.The factors for ischemic and hemorrhagic stroke are not the same.