非淋菌性泌尿生殖道炎病原学及支原体药敏检测结果分析

目的：了解沙眼衣原体（CT）、解脲支原体（UU）和人型支原体（MH）在非淋菌性泌尿生殖道炎中的病原学作用以及感染支原体的耐药情况。方法：采用英国“立明”沙眼衣原体抗原检测卡沙眼衣原体，采用法国生物－梅里埃公司的Myocoplasma IST试剂盒对支原体进行分型培养及药物敏感性检测，结果：1896例非淋菌性泌尿生殖道炎患者中，沙眼衣原体感染阳性率为43．7％（829／1896）；支原体培养阳性率为35．8％（669／1896），其中UU、MH和UU＋MH感染的阳性率分别为（64．9％（434／669）、3．9％（26／669）和31．2％（209／669）；CT＋支原体混合感染阳性率为8．6％（161／1896）；其它病原体感染阳性率为12．7％（237／1896）。UU及MH两型支原体的敏感药物分别是交沙霉素、原始霉素、强力霉素，两型支原体的耐工药物分别是红霉素、泰利必妥。结论：非淋菌性泌尿生殖道炎的主要病原体为CT及支原体，支原体中以UU为主；支原体对交沙霉素，原始霉素，强力霉素的敏感性高。

Analysis of Nongonococcal Urogenital Tract Infection Etiology and Drug Sensitivity of Mycoplasma

Objective:To study the etiology of nongonococcal urogenital tract infection and drug resistance of mycoplasma.Methods:C-C rapid assay and mycoplasma IST kits were used. Results:829 in 1 896 cases showed chlamydia trachomatis(CT) positive (43.7%). 669 in 1 896 cases showed mycoplasma positive (35.8%). Among mycoplasma,UU,MH and UU+MH positive rates were 64.9%(434/669), 3.9 %(26/669) and 31.2%(209/669)respectively. 161 in 1 896 cases were CT+mycoplasma(8.6%).Other pathogens were 237 cases (12.7%).The sensitive antibiotics of mycoplasma were josamycin, pristinamycin, doxycycline. Conclusion:The major pathogens of the nongonococcal urogenital tract infection were CT and UU. Josamycin, pristinamycin, and doxycycline may be the first drugs selected to treat mycoplasma infection.