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颈动脉系统短暂性脑缺血发作与颅内外血管狭窄的相关研究
引用本文:袁毅,李慎茂,朱凤水,支兴龙,吉训民.颈动脉系统短暂性脑缺血发作与颅内外血管狭窄的相关研究[J].中南大学学报(医学版),2008,33(8):751-754.
作者姓名:袁毅  李慎茂  朱凤水  支兴龙  吉训民
作者单位:1.中南大学湘雅三医院神经内科,长沙 410013; 2.首都医科大学宣武医院神经外科,北京 100053
摘    要:目的:探讨颈动脉系统短暂性脑缺血发作(transient ischemic attacks,TIA)的临床特点和颅内外血管狭窄的关系.方法:对52例颈动脉系统TIA患者进行数字减影血管造影(digital subtraction angiography,DSA)检查,观察受累血管的部位及狭窄程度.结果:52例患者中45例(86.5%)存在不同程度的颅内外血管病变,其中29例(64.4%)病人存在2处以上血管狭窄,血管重度狭窄或闭塞多见于短时程(发作持续时间<1h)和多次发作(发作频率≥2)TIA.结论:颈动脉系统TIA患者大多存在颅内外血管狭窄,短时程和多次发作TIA常伴有血管严重狭窄或闭塞,DSA检查有助于明确TIA的血管性病因,并对治疗方法的选择提供指导.

关 键 词:颈动脉系统  颅内外血管狭窄  短暂性脑缺血发作  数字减影血管造影  
收稿时间:2007-3-6

Correlative study of carotid transient ischemic attacks and intracranial or extracranial angiostenosis
YUAN Yi,LI Shen-mao,ZHU Feng-shui,ZHI Xing-long,JI Xun-min.Correlative study of carotid transient ischemic attacks and intracranial or extracranial angiostenosis[J].Journal of Central South University (Medical Sciences)Journal of Central South University (Medical Sciences),2008,33(8):751-754.
Authors:YUAN Yi  LI Shen-mao  ZHU Feng-shui  ZHI Xing-long  JI Xun-min
Institution:1.Department of Neurology, Third Xiangya Hospital, Central South University, Changsha 410013;
2. Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing 100053, China
Abstract:Objective To investigate the relationship between the clinical features of carotid transient ischemic attacks (TIA) and the intracranial or extracranial angiostenosis.Methods Location and degree of stenosis of involved arteries were examined by the digital subtraction angiography in 52 patients with carotid TIA.Results Intracranial or extracranial vascular lesions of different degrees were revealed in 45 patients (86.5%), and 29 out of 45 (64.4%) had more than one site. Severe stenosis and occlusion occurred more frequently in TIA patients with short duration(less than 1 hour) and multiple attacks (more than twice).Conclusion Most patients with TIA of carotid systems have stenosis in intracranial or extracranial arteries. TIA with short duration and multiple attacks always accompany with severe stenosis or occlusion in intracranial or extracranial arteries. Digital subtraction angiography helps to identify the vascular etiology of TIA and provides the instruction of therapeutic regimen.
Keywords:carotid systems  intracranial or extracranial artery stenosis  transient ischemic attacks  digital subtraction angiography
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