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雷诺病血小板聚集特性及血浆vWFAg浓度观察
引用本文:张广森,凌柱三,夏锦如.雷诺病血小板聚集特性及血浆vWFAg浓度观察[J].中南大学学报(医学版),1988(4).
作者姓名:张广森  凌柱三  夏锦如
作者单位:湖南医学院第二附属医院内科 (张广森,凌柱三),湖南医学院第二附属医院内科(夏锦如)
摘    要:本文报道5例雷诺病的血小板聚集功能及血浆vWFAg浓度观察结果。雷诺病血小板对肾上腺素诱聚的反应性显著增高,80%的病例血小板对ADP诱聚存在高反应性。全部病例血浆vWFAg浓度明显增加。提示雷诺病存在血小板高反应性及血管内膜的损伤。

关 键 词:雷诺病  血小板聚集  von  Willebrand因子  血液

PLATLET AGGREGATION AND PLASMA vWFAg LEVEL IN RAYNAUD'S DISEASE-5 CASES
Zhang Guangsen Lin Chusan Xia Jinru Internal Medicine,The Second Affiliated Hospital.PLATLET AGGREGATION AND PLASMA vWFAg LEVEL IN RAYNAUD''''S DISEASE-5 CASES[J].Journal of Central South University (Medical Sciences)Journal of Central South University (Medical Sciences),1988(4).
Authors:Zhang Guangsen Lin Chusan Xia Jinru Internal Medicine  The Second Affiliated Hospital
Abstract:Platelet aggregation function and plasma vwFAg level in 5 patients with Raynaud's disease were investigated. Adrenal and 80% of ADP induced platelet aggregation was enhanced. All plasma vWFAg level was significantly increased(P<0.001).The result suggested that platelet hyperactivity and vascular endothelialdamage play a role in the pathogenesis of Raynaud's disease.
Keywords:von willebrand factor  blood  Raynaud's disease  platelet aggregation
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