新疆维吾尔族、哈萨克族外周动脉疾病患病率及危险因素分析

目的 了解新疆维吾尔族(维族)、哈萨克族(哈族)成年人外周动脉疾病(PAD)的患病率和相关危险因素.方法 2007年10月至2010年5月应用整群抽样法抽取新疆35岁以上汉族、维族、哈族人群14 618名作为研究对象.统计不同民族不同年龄、不同性别人群的PAD患病率,并对PAD的危险因素进行分析.结果 新疆维族、哈族成年人PAD总患病率6.46%(542例),标化患病率6.51%.维族PAD患病率7.05%(315例),哈族为5.79%(227例),经标化后,维族、哈族患病率分别为7.08%、5.83%,差异有统计学意义(x2=5.55,P＜0.05).男性患病率4.49%(170例),女性为8.08%(372例),经标化后,男性患病率为4.30%,女性为7.90%,差异有统计学意义(x2=44.26,P＜0.01).经多因素Logistic回归分析,年龄(OR=1.01,95%CI1.00～1.02)、女性(OR=1.75,95%CI1.45～2.14)、肥胖或超重(OR=1.04,95%CI1.01～1.06)、糖尿病(OR=1.59,95%CI 1.01～2.36)、收缩压增高(OR=1.02,95%CI1.01～1. 03)、舒张压增高(OR=1. 08,95%CI 1.01～1.11)、冠心病史(OR=1.69,95%CI1.14～2.50)与PAD患病有关.结论 新疆维、哈族成年人PAD患病率较低.女性、年龄、超重或肥胖、糖尿病、收缩压升高、舒张压升高、冠心病史为PAD危险因素.

Prevalence of peripheral arterial disease and its correlative risk factors in Xinjiang Uygur and Kazak adult populations

Objective To investigate the prevalence of peripheral arterial disease (PAD) and its correlative risk factors in Xinjiang Uygur and Kazak adult populations. Methods The subjects over the age of 35 years old in Urumqi, Karamay City, Fukang City, Turpan Region, Hotan Prefecture and Yili Kazak Autonomous Prefecture were selected by the four-stage random sampling method. The investigators collected the data of PAD prevalence in different nationalities, different age groups and different gender groups and analyzed its risk factors. Results The prevalence of PAD in Uygur and Kazak adults was 6. 46% (n =542). The standardized prevalence was 6. 51%. The prevalence of PAD was 7.05% (n = 315 )in Uygur adults and 5.79% ( n = 227 ) in Kazak adults. The standardized prevalence in the Uygur and Kazak adults was 7. 08% and 5.83% respectively. The prevalence of PAD of different nationalities was different ( x2 =5.55, P＜0.05). And its prevalence was4.49% (n=170) in males and 8.08% (n=372) in females.The standardized prevalence was 4. 30% in males and 7. 90% in females. The prevalence of PAD in males and females was significantly different ( x2 = 44. 26, P ＜ 0. 01 ). The multivariate logistic regression analysis was performed. Age ( OR = 1. 01, 95% CI 1.00 - 1.02 ), females ( OR = 1.75, 95% CI 1.45 - 2. 14 ),overweight or obesity( OR = 1.04, 95% CI 1.01 - 1.06 ), diabetes ( OR = 1. 59, 95% CI 1. 01 - 2. 36 ),elevated systolic blood pressure( OR = 1. 02, 95% CI 1.01 - 1.03 ), elevated diastolic blood pressure( OR =1.08, 95% CI 1.01 - 1.11 ) and history of coronary heart disease ( OR = 1. 69,95% CI 1.14 - 2. 50) were associated with an elevated prevalence of PAD. Conclusion The prevalence of PAD is lower in Xinjiang Uygur and Kazak adult populations. Females, age, overweight or obesity, diabetes, elevated systolic blood pressure and a history of coronary heart disease are risk factors of PAD.