含钙、镁生物敷料对氢氟酸烧伤后大鼠血钙浓度的影响

目的:应用我们制备的含钙、镁合剂生物敷料,覆盖大鼠氢氟酸烧伤创面,观察血钙浓度变化,探讨其作用效果.找到一种使用方便,经济,安全,能快速阻断氟离子对组织损害、保护间生态组织的方法.方法:以Wistar大鼠为动物模型,设A组为正常对照组;B组为烧伤后不治疗组;C组为烧伤后应用钙剂湿敷组;D组为烧伤后应用含钙、镁生物敷料组.分别于伤后4小时、8小时、24小时、72小时抽血,测定血钙浓度.结果:钙、镁生物敷料组组织损伤较轻,死亡率低,血钙浓度降低较小.而钙剂湿敷组与不治疗组无明显差别.结论:应用钙、镁生物敷料可有效地阻断氟离子的进行性损害,保护间生态组织,减少低血钙的发生.

Influence of the Large Mouse's Density of Blood Calcium after Including the Calcium , Biological Dressing of Magnesium and Burning to the Hydr-ofluoric Acid

Objective:The ones that used us to prepare include the calcium, biological dressing of magnesium mixture, covered the hydrofluoric acid of big mouse and burnt the surface of a wound, observe the density of blood calcium to change, probe into its function result. Finding one easy to use, economy is safe, can block Fluorine ion and damage, protect a ecology to organize the method to the organization fast .Methods:Regard big mouse of Wistar as animal's model, set up group A and contrast the group normally; Group B does not treat the group after burning; C group use calcium to be magnesium pharmaceutical wet to apply group after burning; Group D uses including the calcium, magnesium biological dressing group after burning. 4 hours after being wounded separately, blooding drawing 8 hours, 24 hours, 72 hours, determine the density of blood calcium. Results:Calcium , magnesium biological dressing group is it damage relatively light to organize, death rate low, blood calcium it is light for density to reduce. Calcium pharmaceutical wet to apply group with treat group have obvious difference. Conclusion: Use calcium, magnesium biological dressing can block person who go on, Fluorine of ion damage effectively, protect a ecology to organize, reduce the emergence of the low blood calcium.