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山楂叶总黄酮活血化瘀作用实验研究
引用本文:杨宇杰,董晓强,郭金甲.山楂叶总黄酮活血化瘀作用实验研究[J].河北医学,2009,15(1):22-23.
作者姓名:杨宇杰  董晓强  郭金甲
作者单位:1. 承德医学院,河北,承德,067000
2. 承德颈复康药业集团有限公司,河北,承德,067000
摘    要:目的:观察山楂叶总黄酮(HawthornLeavesFlavonoids,HLF)活血化瘀作用。方法:采用体内血栓形成、血小板聚集、微循环、血液流变学测定等方法。结果:HLF可显著抑制大鼠血栓形成,抑制ADP诱导的小鼠血小板体外聚集,显著改善小鼠耳廓微循环状态,降低大鼠血液粘度。结论:HLF具有良好的活血化瘀作用。

关 键 词:山楂叶总黄酮  血栓  血小板聚集  微循环

Experimental Research of Blood-quickening Stasis-transforming Actions of Hawthorn Leaf Flavonoids
YANG Yu-jie,et al.Experimental Research of Blood-quickening Stasis-transforming Actions of Hawthorn Leaf Flavonoids[J].Hebei Medicine,2009,15(1):22-23.
Authors:YANG Yu-jie  
Institution:YANG Yu-jie, et al ( Chengde Medical College, Hebei Chengde 067000, China)
Abstract:Objective: To investigate the blood-quickening stasis-transforming actions of hawthorn leaf flavonoids in different circles.Method: The methods of formation of thrombin in vivo,aggregation of platelets and microcirculation were used.Result: Hawthorn leaf flavonoids could obviously inhibit formation of thrombin,inhibit platelet aggregation induced by ADP,improve the microcirculation blood-quickening and stasis-transforming actions significantly.Conclusion: Hawthorn leaf flavonoids possesses obvious actions of blood-quickening and stasis-transforming.
Keywords:Hawthorn leaf flavonoids  Thrombin  Platelet aggregation  Microcirculation  
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