参附注射液对慢性心力衰竭患者心功能及血常规指标的影响

目的：：探讨参附注射液对慢性心力衰竭患者心功改善及血脑钠肽( BNP )水平和血常规指标红细胞体积分布宽度( RDW)、红细胞压积( HCT)、血小板压积( PCT)的影响。方法：慢性心力衰竭患者60例随机分为对照组和参附治疗组，各30例。对照组使用常规药物进行治疗，参附治疗组在常规药物治疗基础上加用参附注射液。观察两组治疗前后心功能改变及血BNP 水平和血常规指标RDW、HCT、PCT的变化。结果：参附治疗组总有效率(93.3％)明显高于对照组(70.0％)，且治疗后血 BNP、RDW、HCT、PCT水平均较治疗前降低，差异有统计学意义( P<0.05)；两组治疗后血BNP 及RDW水平比较，差异有统计学意义(P<0.05)，HCT、PCT比较差异无统计学意义(P>0.05)。结论：参附注射液对慢性心力衰竭患者的心功能改善有一定作用，降低血BNP、RDW、HCT、PCT水平，可作为临床治疗心力衰竭的一项选择。

Effect of Shenfu Injection on Cardiac Function and Blood Index in Patients with Chronic Heart Failure

Objective: To observe the effect of Shenfu injection on cardiac function and BNP、RDW、HCT、PCTlevel in patients with chronic heart failure. Methods:Sixty patients with chronic heart failure were randomly divided into two groups,30 cases in each group. The control group treated with conventional treat-ment,and treatment group treated with conventional treatment and Shenfu injection. The cardiac function and plasma BNP、RDW、HCT、PCT were measured before and after treatment. Results: Compared with control group,the total efficiency of treatment group (93.3%) was significantly higher (70.0%); after treatment,the concentration of plasma BNP 、RDW、HCT、PCT levels lower than before treatment, the difference was statisti-cally significant ( P <0.05);after treatment were compared blood levels of BNP and RDW in two group, the difference was statistically significant (P<0.05),but HCT and PCT,statistics have no significant differences (P>0.05).Conclusion:Shenfu injection could improve cardiac function in patients with chronic heart failure and lower level of plasma BNP、RDW、HCT and PCT,it can be as an option for the clinical treatment of heart failure.